Results 21 to 30 of about 1,102,167 (387)
Animals, 2022 Semen cryopreservation is very important in animal agriculture to maximize the number of daughters of genetically superior males and to distribute the cryopreserved semen of good males all over the world.
Mohamed Shehab-El-Deen +2 more
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Cysteine depletion induces pancreatic tumor ferroptosis in mice
Science, 2020 Ferroptotic cell death and cancer Cell death can occur through different mechanisms, several of which are being explored as potential targets for cancer treatment.
Michael A. Badgley +29 more
semanticscholar +1 more source
Cysteine residues in signal transduction and its relevance in pancreatic beta cells
Frontiers in Endocrinology, 2023 Cysteine is one of the least abundant but most conserved amino acid residues in proteins, playing a role in their structure, metal binding, catalysis, and redox chemistry.
Blanka Holendova, Lydie Plecita-Hlavata
doaj +1 more source
bioRxiv, 2021 As one of the three mammalian gasotransmitters, hydrogen sulfide (H2S) plays a major role in maintaining physiological homeostasis. Endogenously produced H2S plays numerous beneficial roles including mediating vasodilation and conferring neuroprotection.
Domenick J. Braccia +3 more
semanticscholar +1 more source
Understanding the role of cysteine in ferroptosis: progress & paradoxes
The FEBS Journal, 2021 Cysteine is a conditionally essential amino acid required for the synthesis of proteins and many important intracellular metabolites. Cysteine depletion can trigger iron‐dependent nonapoptotic cell death–ferroptosis.
Carson D. Poltorack, S. Dixon
semanticscholar +1 more source
The Homology Modeling and Docking Investigation of Human Cathepsin B [PDF]
International Journal of Medical Toxicology and Forensic Medicine, 2020 Background: Cathepsin B comprises a group of lysosomal cysteine proteases belonging to the Papain family; it has an intracellular function in the process of protein catabolism, antigen processing in the immune response, and Alzheimer’s disease.
Afshin Khara +2 more
doaj +1 more source
Non-canonical glutamate-cysteine ligase activity protects against ferroptosis
bioRxiv, 2020 Cysteine is required for maintaining cellular redox homeostasis in both normal and transformed cells. Deprivation of cysteine induces the iron-dependent form of cell death known as ferroptosis; however, the metabolic consequences of cysteine starvation ...
Y. Kang +4 more
semanticscholar +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Acute kidney injury (AKI) is a major risk factor for chronic kidney disease and increased mortality. Until now, no compelling preventive or therapeutic strategies have been identified. Dietary interventions have been proven highly effective in
Thomas Osterholt +12 more
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Cysteine and homocysteine as biomarker of various diseases
Food Science & Nutrition, 2020 Cysteine and homocysteine (Hcy), both sulfur‐containing amino acids (AAs), produced from methionine another sulfur‐containing amino acid, which is converted to Hcy and further converted to cysteine.
Tahniat Rehman +9 more
semanticscholar +1 more source
Succination of Protein Thiols in Human Brain Aging
Frontiers in Aging Neuroscience, 2020 Human brain evolution toward complexity has been achieved with increasing energy supply as the main adaptation in brain metabolism. Energy metabolism, like other biochemical reactions in aerobic cells, is under enzymatic control and strictly regulated ...
Mariona Jové +7 more
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