Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. [PDF]
, 2015 Frizzled is the earliest discovered glycosylated Wnt protein receptor and is critical for the initiation of Wnt signaling. Antagonizing Frizzled is effective in inhibiting the growth of multiple tumor types.
Baday, Yiressy C +9 more
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An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein [PDF]
, 2005 Campylobacter jejuni is a Gram-negative food-borne pathogen associated with gastroenteritis in humans as well as cases of the autoimmune disease Guillain Barre syndrome. C.
Altekruse +61 more
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Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water
Science, 2020 Cysteine as peptide precursor and catalyst Among amino acids, cysteine is highly reactive as a nucleophile, metal ligand, and participant in redox and radical reactions. These properties make cysteine attractive as a component of prebiotic chemistry, but
Callum S. Foden +5 more
semanticscholar +1 more source
Acta Universitatis Sapientiae: Alimentaria, 2018 The research subject is the elaboration of a method and procedure for processing feather from poultry slaughterhouses and using it as antioxidant as well as for satisfying the sulphurous amino acid needs of ruminants.
Csapó J., Albert Cs.
doaj +1 more source
A Disulfide Bond in the Membrane Protein IgaA Is Essential for Repression of the RcsCDB System
Frontiers in Microbiology, 2017 IgaA is an integral inner membrane protein that was discovered as repressor of the RcsCDB phosphorelay system in the intracellular pathogen Salmonella enterica serovar Typhimurium.
M. Graciela Pucciarelli +4 more
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Stable isotopes to study sulfur amino acid utilization in broilers
Animal, 2020 Nutritionists have been discussing whether the dietary supplementation of cyst(e)ine is required as a part of the dietary methionine (Met) in the total sulfur amino acid (TSAA) requirement to achieve optimum performance in broilers.
R.M. Suzuki +8 more
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Cysteine-Mediated Extracellular Electron Transfer of Lysinibacillus varians GY32
Microbiology Spectrum, 2022 Microbial extracellular electron transfer (EET) is essential in many natural and engineering processes. Compared with the versatile EET pathways of Gram-negative bacteria, the EET of Gram-positive bacteria has been studied much less and is mainly limited
Guannan Kong +9 more
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Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo [PDF]
, 2007 Cysteine proteinases from the fruit and latex of plants, including papaya, pineapple and fig, were previously shown to have a rapid detrimental effect, in vitro, against the rodent gastrointestinal nematodes, H eligmosomoides polygyrus (which is found in
Behnke, J.M. +4 more
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Cysteine and Cysteine-Related Signaling Pathways in Arabidopsis thaliana [PDF]
Molecular Plant, 2014 Cysteine occupies a central position in plant metabolism because it is a reduced sulfur donor molecule involved in the synthesis of essential biomolecules and defense compounds. Moreover, cysteine per se and its derivative molecules play roles in the redox signaling of processes occurring in various cellular compartments. Cysteine is synthesized during
Romero González, Luis Carlos +5 more
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Free Radical Biology and Medicine, 2015 The cysteine (Cys) proteome is a major component of the adaptive interface between the genome and the exposome. The thiol moiety of Cys undergoes a range of biologic modifications enabling biological switching of structure and reactivity. These biological modifications include sulfenylation and disulfide formation, formation of higher oxidation states,
Go, Young-Mi +2 more
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