Results 51 to 60 of about 1,102,167 (387)

Cysteine Cathepsins and Their Extracellular Roles: Shaping the Microenvironment

Cells, 2019
For a long time, cysteine cathepsins were considered primarily as proteases crucial for nonspecific bulk proteolysis in the endolysosomal system. However, this view has dramatically changed, and cathepsins are now considered key players in many important
Eva Vidak, Urban Javoršek, Matej Vizovišek, B. Turk   +3 more
semanticscholar   +1 more source

Negative modulation of the GABAAρ1 receptor function by l-cysteine [PDF]

, 2017
l-Cysteine is an endogenous sulfur-containing amino acid with multiple and varied roles in the central nervous system, including neuroprotection and the maintenance of the redox balance.
Beltrán González, Andrea Natalia, Calvo, Daniel Juan, Vicentini, Florencia   +2 more
core   +1 more source

On cysteine and cystine peptides. Part V. S-trityl- and S-diphenylmethyl-cysteine and -cysteine peptides

Journal of the Chemical Society C: Organic, 1970
A new method for the preparation of S-trityl-(i.e. triphenylmethyl) and S-diphenylmethyl-cysteines or -cysteine peptides involves treatment of cysteine or cysteine peptides with aralkylcarbinols in the presence of trifluoroacetic acid or hydrogen halides in acetic acid solution.
Photaki, I., Taylor-Papadimitriou, J., Sakarellos, C., Mazarakis, P., Zervas, L.   +4 more
openaire   +3 more sources

Floret Biofortification of Broccoli Using Amino Acids Coupled with Selenium under Different Surfactants: A Case Study of Cultivating Functional Foods

Plants, 2023
Broccoli serves as a functional food because it can accumulate selenium (Se), well-known bioactive amino-acid-derived secondary metabolites, and polyphenols.
Dimitris L. Bouranis, Georgios P. Stylianidis, Vassiliki Manta, Evangelos N. Karousis, Andriani Tzanaki, Despina Dimitriadi, Emmanuel A. Bouzas, Vassilis F. Siyiannis, Violetta Constantinou-Kokotou, Styliani N. Chorianopoulou, Elke Bloem   +10 more
doaj   +1 more source

Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]

, 2012
At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P., Guisez, Y., Lejon, V., Rogé, S., Van Nieuwenhove, L.   +4 more
core   +1 more source

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols [PDF]

, 2009
It has been previously proposed that nitric oxide (NO) is the only biologically relevant nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However, recent reports implicate HNO as another possible activator of sGC.
Adrian J. Hobbs, Anderegg, Andrea J. Lee, Bari, Bartberger, Bermejo, Bonner, Brandwein, Burstyn, Craven, Craven, De Witt, DeMaster, Denninger, Derbyshire, DeRubertis, Dierks, Doyle, Drago, Dutton, Dutton, Ellis, Ellis, Farmer, Favaloro, Feelisch, Fukuto, Fukuto, Haddox, Halliwell, Hobbs, Hoshino, Ignarro, Ignarro, Ignarro, Ignarro, Immoos, Irvine, Irvine, Jon M. Fukuto, Judith N. Burstyn, Kamisaki, Katrina M. Miranda, Kim, Lin, Lopez, Maragos, Melisa M. Cherney, Miranda, Miranda, Miranda, Nestor E. Francoleon, Niederhoffer, Paolocci, Paolocci, Patrick J. Farmer, Pervitsky, Pino, Poulos, Rusche, S. Bruce King, Sayed, Scheidt, Schmidt, Serfass, Sha, Shafirovich, Shahidullah, Shen, Smith, Stasch, Stone, Stone, Sulc, Sulc, Thadani, Thomas W. Miller, Turk, Väänänen, Väänänen, Wanstall, Wayland, Wayland, Wolin, Wong, Yonetani   +85 more
core   +2 more sources

The Non-Essential Amino Acid Cysteine Becomes Essential for Tumor Proliferation and Survival

Cancers, 2019
The non-essential amino acid cysteine is used within cells for multiple processes that rely on the chemistry of its thiol group. Under physiological conditions, many non-transformed tissues rely on glutathione, circulating cysteine, and the de novo ...
Joseph A. Combs, G. DeNicola
semanticscholar   +1 more source

Electroanalytical Determination of Cysteine Using the Electrodes Based on Ternary Silver-Copper Sulfides

Sensors, 2018
The amperometric determination of cysteine, using an electrode based on ternary silver-copper sulfide, is presented. Electrochemical characterizations (using cyclic voltammetry) of three electrode materials revealed that the electrode based on the ...
Nives Vladislavić, Ivana Škugor Rončević, Maša Buljac, Slobodan Brinić, Denis Krivić, Marijo Buzuk   +5 more
doaj   +1 more source

Comparative Study of a Series of ^99mTc(CO)₃ Mannosylated Dextran Derivatives for Sentinel Lymph Node Detection

Molecules, 2021
Sentinel lymph node detection (SLND) is rapidly entering common practice in the management of patients with tumors. The introduction of mannose molecules to 99mTc-labeled dextrans, so far, showed that the sentinel node could trap these agents due to ...
Afroditi Papasavva, Antonio Shegani, Christos Kiritsis, Ioanna Roupa, Myrto Ischyropoulou, Konstantina Makrypidi, Irineos Pilatis, George Loudos, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis   +10 more
doaj   +1 more source

In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. [PDF]

, 2010
BackgroundCruzain, the major cysteine protease of Trypanosoma cruzi, is an essential enzyme for the parasite life cycle and has been validated as a viable target to treat Chagas' disease.
Brinen, Linda S, Chen, Yen Ting, Doyle, Patricia S, Hansell, Elizabeth, Kerr, Iain D, McKerrow, James H, Roush, William R   +6 more
core   +3 more sources