Results 181 to 190 of about 47,940 (359)

An endogenous inhibitor of cysteine and serine proteinases from spleen [PDF]

FEBS Letters, 1982
Vito Turk, M. Kopitar, P. Ločnikar, J. Brzin   +3 more
openaire   +3 more sources

Proteolysis-induced pathomechanisms in acute inflammation and related therapeutic approaches [PDF]

, 1991
A Billing, A Billing, B Blauhut, C Gippner-Steppert, D Inthorn, D Nast-Kolb, H Hoffmann, H Vinazzer, I Assfalg-Machleidt, I Schraufstatter, JI Weitz, K-H Duswald, M Jochum, M Jochum, M Jochum, M Jochum, M Jochum, M Jochum, M Jochum, M Jochum, M Siebeck, M Siebeck, M Spannagl, MD Wewers, RE Jordan, S Idell, S Neumann, TE Emerson, U Obertacke, YT Wachtfogel, YT Wachtfogel   +30 more
core   +1 more source

Potencial biotecnológico das cistatinas [PDF]

, 2011
bitstream/CNPA/19714/1/DOC109 ...
VIDAL, M. S.
core  

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, EarlyView.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

The Squamous Cell Carcinoma Antigen 2 Inhibits the Cysteine Proteinase Activity of a Major Mite Allergen, Der p 1 [PDF]

, 2004
Yasuhisa Sakata, Kazuhiko Arima, Toshiro Takai, Wataru Sakurai, Kiyonari Masumoto, Noriko Yuyama, Yoshinori Suminami, Fumio Kishi, Tetsuji Yamashita, Takeshi Kato, Hideoki Ogawa, Kazuma Fujimoto, Yo Matsuo, Yuji Sugita, Kenji Izuhara   +14 more
openalex   +1 more source

Redirecting the Peptide Cleavage Causes Protease Inactivation

Angewandte Chemie International Edition, Accepted Article.
Cysteine and serine proteases cleave peptides through covalent catalysis by generating a transient adduct with the N‐terminal part of the substrate after releasing its C‐terminal part. We demonstrate the unique redirection of this event leading to strong enzyme inactivation.
Michael Gütschow, Christian Breuer, Jim Küppers, Anna-Christina Schulz-Fincke, Anna Heilos, Carina Lemke, Petra Spiwokowá, Janina Schmitz, Laura Cremer, Marta Frigolé-Vivas, Michael Lülsdorff, Matthias D. Mertens, Filip Wichterle, Miloš Apeltauer, Martin Horn, Erik Gilberg, Norbert Furtmann, Jürgen Bajorath, Ulrike Bartz, Bernd Engels, Michael Mareš   +20 more
wiley   +1 more source

Establishment, optimization and validation of a fluorescence polarization-based high-throughput screening assay targeting cathepsin L inhibitors

SLAS Discovery
Cathepsin L (CTSL), a lysosomal cysteine proteinase, is primarily dedicated to the metabolic turnover of intracellular proteins. It is involved in various physiological processes and contributes to pathological conditions such as viral infection, tumor ...
Wenwen Zhou, Baoqing You, Xiaomeng Zhao, Shuyi Si, Yan Li, Jing Zhang   +5 more
doaj  

Aprotinin and its target enzymes in vitro and in vivo [PDF]

, 1990
Birnbaum, B., Fritz, Hans, Hoffmeister, H., Jochum, Marianne   +3 more
core   +1 more source

Metal‐Mediated Protein Engineering within Live Cells

Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.
This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley   +1 more source

Use of inhibitors to identify essential cysteine proteinases of Trichomonas vaginalis [PDF]

, 2006
Joseph W. Irvine, Michael North, Graham H. Coombs   +2 more
openalex   +1 more source