Results 11 to 20 of about 108,777 (376)

Cystatins — Inhibitors of Cysteine Proteinases [PDF]

open access: yesCritical Reviews in Oral Biology & Medicine, 1992
The cystatin superfamily of proteins, derived from a common ancestor, is comprised of a diverse group of potent cysteine proteinase inhibitors and antibacterial/viral agents grouped into several families. This review concentrates on family 2 cystatins, namely, the human salivary cystatins and cystatin C.
L A, Bobek, M J, Levine
openaire   +2 more sources

Melia azedarach L. extract induced the production of phytocystatin in passion fruit leaves

open access: yesHoehnea, 2021
Phytocystatins belong to the family of cysteine proteinases inhibitors. These proteinase inhibitors have crucial functions in plant defense against insects and pathogens attack. In the present study Melia azedarach L. extract acts as an elicitor of plant
Alyne Bispo Rodrigues   +1 more
doaj   +1 more source

Repurposing Anti-Dengue Compounds against Monkeypox Virus Targeting Core Cysteine Protease

open access: yesBiomedicines, 2023
The monkeypox virus (MPXV) is an enveloped, double-stranded DNA virus belonging to the genus Orthopox viruses. In recent years, the virus has spread to countries where it was previously unknown, turning it into a worldwide emergency for public health ...
Mohd Imran   +9 more
doaj   +1 more source

Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin.

open access: hybridJournal of Biological Chemistry, 1987
Magnus Abrahamson   +5 more
openalex   +2 more sources

Vacuolar Processing Enzymes Modulating Susceptibility Response to Fusarium oxysporum f. sp. cubense Tropical Race 4 Infections in Banana

open access: yesFrontiers in Plant Science, 2022
Fusarium oxysporum f. sp. cubense tropical race 4 (FocTR4) is a destructive necrotrophic fungal pathogen afflicting global banana production. Infection process involves the activation of programmed cell death (PCD).
Wan Muhamad Asrul Nizam Wan Abdullah   +7 more
doaj   +1 more source

Targeting SARS-CoV-2: a systematic drug repurposing approach to identify promising inhibitors against 3C-like proteinase and 2′-O-ribose methyltransferase

open access: yesJournal of Biomolecular Structure and Dynamics, 2020
The recent pandemic associated with SARS-CoV-2, a virus of the Coronaviridae family, has resulted in an unprecedented number of infected people. The highly contagious nature of this virus makes it imperative for us to identify promising inhibitors from ...
Rameez Jabeer Khan   +8 more
semanticscholar   +1 more source

Identification of three stage-specific proteinases of Plasmodium falciparum. [PDF]

open access: yes, 1987
We have identified and characterized three stage-specific proteinases of Plasmodium falciparum that are active at neutral pH. We analyzed ring-, trophozoite-, schizont-, and merozoite-stage parasites by gelatin substrate PAGE and characterized the ...
Kim, K   +3 more
core   +2 more sources

Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]

open access: yes, 2020
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I   +3 more
core   +2 more sources

Cysteine peptidases and their inhibitors in breast and genital cancer.

open access: yesFolia Histochemica et Cytobiologica, 2010
Cysteine proteinases and their inhibitors probably play the main role in carcinogenesis and metastasis. The metastasis process need external proteolytic activities that pass several barriers which are membranous structures of the connective tissue which ...
Magdalena Milan   +7 more
doaj   +1 more source

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