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Cystatins — Inhibitors of Cysteine Proteinases [PDF]
The cystatin superfamily of proteins, derived from a common ancestor, is comprised of a diverse group of potent cysteine proteinase inhibitors and antibacterial/viral agents grouped into several families. This review concentrates on family 2 cystatins, namely, the human salivary cystatins and cystatin C.
L A, Bobek, M J, Levine
openaire +2 more sources
Melia azedarach L. extract induced the production of phytocystatin in passion fruit leaves
Phytocystatins belong to the family of cysteine proteinases inhibitors. These proteinase inhibitors have crucial functions in plant defense against insects and pathogens attack. In the present study Melia azedarach L. extract acts as an elicitor of plant
Alyne Bispo Rodrigues +1 more
doaj +1 more source
Repurposing Anti-Dengue Compounds against Monkeypox Virus Targeting Core Cysteine Protease
The monkeypox virus (MPXV) is an enveloped, double-stranded DNA virus belonging to the genus Orthopox viruses. In recent years, the virus has spread to countries where it was previously unknown, turning it into a worldwide emergency for public health ...
Mohd Imran +9 more
doaj +1 more source
High molecular weight cysteine proteinase inhibitors in Atlantic salmon and other fish species [PDF]
Olonen, Anne
core +2 more sources
Fusarium oxysporum f. sp. cubense tropical race 4 (FocTR4) is a destructive necrotrophic fungal pathogen afflicting global banana production. Infection process involves the activation of programmed cell death (PCD).
Wan Muhamad Asrul Nizam Wan Abdullah +7 more
doaj +1 more source
The recent pandemic associated with SARS-CoV-2, a virus of the Coronaviridae family, has resulted in an unprecedented number of infected people. The highly contagious nature of this virus makes it imperative for us to identify promising inhibitors from ...
Rameez Jabeer Khan +8 more
semanticscholar +1 more source
Identification of three stage-specific proteinases of Plasmodium falciparum. [PDF]
We have identified and characterized three stage-specific proteinases of Plasmodium falciparum that are active at neutral pH. We analyzed ring-, trophozoite-, schizont-, and merozoite-stage parasites by gelatin substrate PAGE and characterized the ...
Kim, K +3 more
core +2 more sources
Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I +3 more
core +2 more sources
Cysteine peptidases and their inhibitors in breast and genital cancer.
Cysteine proteinases and their inhibitors probably play the main role in carcinogenesis and metastasis. The metastasis process need external proteolytic activities that pass several barriers which are membranous structures of the connective tissue which ...
Magdalena Milan +7 more
doaj +1 more source

