Results 21 to 30 of about 70 (65)

Human cysteine proteinase inhibitors

Scandinavian Journal of Clinical and Laboratory Investigation, 1988
Magnus Abrahamson
exaly   +2 more sources

Novel Cysteine Proteinase Inhibitors Homologous to the Proregions of Cysteine Proteinases

Current Protein & Peptide Science, 2002
Propeptides of papain-like cysteine proteinases such as papain, cathepsins B, L and S are potent inhibitors of their cognate cysteine proteinases with Ki values in the nanomolar range, and they exhibit highest inhibition selectivity for enzymes from which they originate. Recent studies have identified novel inhibitor proteins that are homologous to the
Y, Yamamoto, M, Kurata, S, Watabe, R, Murakami, S Y, Takahashi   +4 more
openaire   +2 more sources

Cysteine proteinase inhibitors in human placenta

Placenta, 1985
When human placental extract was chromatographed on a Sephadex G-75 column, cysteine proteinase inhibitors with molecular weights of 80 000 and 12 300 were eluted. The high molecular weight peak (CPI-H) was identified as alpha-cysteine proteinase inhibitor.
M, Warwas, G, Sawicki
openaire   +2 more sources

Cysteine proteinase inhibitor levels in semen

Clinical Biochemistry, 1986
New proteinase inhibitors have recently been found in seminal plasma which specifically inhibit cysteine proteinases such as ficin, papain, cathepsin H and cathepsin B. The inhibitors consist of two components, In-A and In-B, both of which are effective in native semen.
K, Minakata, M, Asano, O, Yonekawa
openaire   +2 more sources

Cysteine proteinase inhibitors in psoriatic epidermis

Archives of Dermatological Research, 1983
Human psoriatic epidermis and scales were demonstrated to contain two antigenically separate cysteine proteinase inhibitors, one acidic with an isoelectric point of 4.7-5.0 (ACPI) and one neutral with an isoelectric point of 6.0-6.5 (NCPI), while normal epidermis contains only ACPI.
V K, Hopsu-Havu, I A, Joronen, M, Järvinen, A, Rinne   +3 more
openaire   +2 more sources

Osteoclastogenesis is decreased by cysteine proteinase inhibitors

Bone, 2004
The effects of cystatin C and other cysteine proteinase inhibitors on osteoclast formation and differentiation have been investigated. Cystatin C decreased osteoclast formation stimulated by parathyroid hormone (PTH), 1,25(OH)2-vitamin D3 or interleukin-6 (IL-6) (in the presence of its soluble receptor) as assessed by the number of tartrate-resistant ...
Monica, Brage, Anita, Lie, Maria, Ransjö, Franciszek, Kasprzykowski, Regina, Kasprzykowska, Magnus, Abrahamson, Anders, Grubb, Ulf H, Lerner   +7 more
openaire   +2 more sources

Bombyx Cysteine Proteinase Inhibitor (BCPI) Homologous to Propeptide Regions of Cysteine Proteinases Is a Strong, Selective Inhibitor of Cathepsin L-like Cysteine Proteinases

Journal of Biochemistry, 2001
Bombyx cysteine proteinase inhibitor (BCPI) is a novel cysteine proteinase inhibitor. The protein sequence is homologous to the proregions of certain cysteine proteinases. Here we report the mechanism of its inhibition of several cysteine proteinases.
M, Kurata, Y, Yamamoto, S, Watabe, Y, Makino, K, Ogawa, S Y, Takahashi   +5 more
openaire   +2 more sources

Cysteine Proteinases and their Inhibitors

1986
Cysteine proteinase inhibitors from fish ...
openaire   +2 more sources

Inhibitors of 3C Cysteine Proteinases from Picornaviridae

Current Topics in Medicinal Chemistry, 2004
The Picornaviridae are among the smallest icosahedral positive-sense single stranded RNA containing viruses known, and comprise one of the largest and most important families of human and animal pathogens. The hepatitis A virus (HAV) and human rhinovirus (HRV) are important pathogens that belong to the picornavirus family.
Manjinder S, Lall, Rajendra P, Jain, John C, Vederas   +2 more
openaire   +2 more sources

Acidic Cysteine Proteinase Inhibitor in Seminal Plasma

Biological Chemistry Hoppe-Seyler, 1985
A cysteine proteinase inhibitor with acidic isoelectric point (pI = 4.7-5.0) was found in human seminal plasma. Its apparent molecular mass is 16 kDa. It inhibits cysteine proteinases like ficin, cathepsin H, cathepsin B and papain. The inhibitory activity of seminal plasma against ficin is almost the same as that of human serum.
K, Minakata, M, Asano
openaire   +2 more sources