Results 11 to 20 of about 753,077 (248)

Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB [PDF]

, 2013
Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping
Mottram, Jeremy C, Mottram Jeremy C., Richard J Marhöfer, Schröder Jörg, Selzer, P.M., Schroder, J., Noack, Sandra, Noack Sandra, Schröder, Jörg, Noack, S., Mottram, J.C., Sandra Noack, Coombs, G.H., Coombs, Graham H, Marhöfer, Richard J, Coombs Graham H., Paul M Selzer, Jeremy C Mottram, Marhöfer Richard J., Marhofer, R.J., Jörg Schröder, Selzer Paul M., Selzer, Paul M, Selzer, Paul M., Graham H Coombs   +24 more
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Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]

, 2013
Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F., Juliano, Luiz, Tersariol, Ivarne L.S., Westrop, Gareth, Almeida, Paulo C, Souza, Gerson A., Judice, W.A.S., Sansevero, Thiago M., Sanderson, Sanya J, Coombs, Graham, Manfredi, Marcella A, Shida, Claudio S.   +11 more
core   +4 more sources

Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]

, 2000
The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard, Valueva, Tatyana A., Revina, Tatyana A., Mosolov, Vladimir V.   +3 more
core   +1 more source

Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity

Virology Journal, 2005
Through the use of transient expression assays and directed genetics, the vaccinia virus (VV) I7L gene product has been implicated as the major maturational proteinase required for viral core protein cleavage to occur during virion assembly.
Hruby Dennis E, Byrd Chelsea M
doaj   +1 more source

Digestive proteolytic activity in the gut and salivary glands of the predatory bug Podisus maculiventris (Heteroptera: Pentatomidae); effect of proteinase inhibitors

European Journal of Entomology, 2005
Proteinase activity in the midgut of the pentatomid stinkbug Podisus maculiventris was investigated. The optimal pH for adult and nymph proteolysis was pH 6.0 and pH 6.5, respectively.
Howard A. BELL, Rachel E. DOWN, John P. EDWARDS, John A. GATEHOUSE, Angharad M.R. GATEHOUSE   +4 more
doaj   +1 more source

Expression of two barley proteinase inhibitors in tomato promotes endogenous defensive response and enhances resistance to Tuta absoluta

BMC Plant Biology, 2018
Background Plants and insects have coexisted for million years and evolved a set of interactions which affect both organisms at different levels. Plants have developed various morphological and biochemical adaptations to cope with herbivores attacks ...
Rim Hamza, Meritxell Pérez-Hedo, Alberto Urbaneja, José L. Rambla, Antonio Granell, Kamel Gaddour, José P. Beltrán, Luis A. Cañas   +7 more
doaj   +1 more source

The tick-derived anticoagulant madanin is processed by thrombin and factor Xa. [PDF]

PLoS ONE, 2013
The cysteine-less peptidic anticoagulants madanin-1 and madanin-2 from the bush tick Haemaphysalis longicornis are the founding members of the MEROPS inhibitor family I53.
Ana C Figueiredo, Daniele de Sanctis, Pedro José Barbosa Pereira   +2 more
doaj   +1 more source

Differential in vitro and in vivo effect of barley cysteine and serine protease inhibitors on phytopathogenic microorganisms [PDF]

, 2011
Protease inhibitors from plants have been involved in defence mechanisms against pests and pathogens. Phytocystatins and trypsin/α-amylase inhibitors are two of the best characterized protease inhibitor families in plants.
Cambra Marin, Ines, Sánchez-Monge Laguna de Rins, Rosa, Diaz Rodriguez, Isabel, Herrero, Ignacio, Carrillo Gil, Laura, Martinez Muñoz, Manuel   +5 more
core   +1 more source

Identification of Proteins Responsible for High Activity of Cysteine Proteinase Inhibitor in the Blood of Nile Tilapia Oreochromis niloticus

Fishes, 2022
Cysteine proteinase inhibitors (CPIs) protect tissues and organs against cysteine proteinases in animal blood and have attracted much attention for use in food processing and medical sciences for humans and animals.
Seong Hee Mun, Joon Yeong Kwon
doaj   +1 more source

Cysteine proteinases and cystatins

Brazilian Archives of Biology and Technology, 2003
This review describeds the definition, localization, functions and examples of cysteine proteinases and their protein inhibitors in vertebrate, non-vertebrate animals and plants. These inhibitors are related with defense mechanisms of plant against pests.
Adeliana S. Oliveira, José Xavier-Filho, Maurício P. Sales   +2 more
doaj   +1 more source