Results 271 to 280 of about 47,940 (359)

Family-wide analysis of human macrodomains reveals novel activities and identifies PARG as most efficient ADPr-RNA hydrolase. [PDF]

Commun Biol
Weixler L, Žaja R, Ikenga NJ, Siefert J, Mohan G, Aydin G, Wijngaarden S, Filippov DV, Lüscher B, Feijs-Žaja KLH.   +9 more
europepmc   +1 more source

Elastase-alpha1-proteinase inhibitor complex [PDF]

, 1984
Bergmeyer, H. U., Bergmeyer, J., Graßl, M., Jochum, Marianne, Neumann, S.   +4 more
core   +1 more source

Myelin Formation by Oligodendrocytes Is Enhanced Through Laminin‐411 and Its Derived Peptide

Glia, EarlyView.
Laminin (LM) α1, α2, and α4 chains are expressed at the myelination stage of oligodendrocyte (OL). LM411 and its E8 fragment enhance OL myelin membrane formation. A4G47 from LM411E8 is a novel peptide that promotes OL myelin formation. ABSTRACT In the central nervous system, oligodendrocytes (OLs) form myelin sheaths that accomplish the efficient ...
Binri Sasaki, Momo Oishi, Tomoka Aoki, Mai Hyodo, Chinami Onchi, Nanako Yamada, Hitomi Misawa, Momona Yamada, Chikako Hayashi, Kiyotoshi Sekiguchi, Keisuke Hamada, Yuji Yamada, Yamato Kikkawa, Motoyoshi Nomizu, Nobuharu Suzuki   +14 more
wiley   +1 more source

<i>Macrovipera lebetinus obtusa</i> Venom and Its Fractions Affect Human Dermal Microvascular Endothelial and Fibrosarcoma Cells. [PDF]

Int J Mol Sci
Ghazaryan N, Van Werven L, Liepold T, Jahn O, Pardo LA, Ayvazyan N.   +5 more
europepmc   +1 more source

Cathepsin B Levels Correlate with the Severity of Canine Myositis. [PDF]

Biomolecules
De Pasquale V, Vaccaro E, Rossin F, Ciampa M, Scarcella M, Paciello O, Tafuri S.   +6 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

To be, or not to be cleaved: Directed evolution of a canonical serine protease inhibitor against active and inactive protease pair identifies binding loop residue critical for prevention of proteolytic cleavage. [PDF]

Protein Sci
Köller Z, Németh BZ, Kiss B, Nagy ZA, Schlosser G, Magyar C, Demcsák A, Sahin-Tóth M, Pál G.   +8 more
europepmc   +1 more source

Underlying Mechanism of Jiuwei Shengmai Powder in Improving Myocardial Hypoxia at High Altitude Based on Network Pharmacology and Molecular Docking

iLABMED, EarlyView.
The expression pathway of COX and the downstream mechanism of PGE. M: muscarinic receptor; PL: phospholipid; PLA2: phospholipase A2; AA: arachidonic acid; EP1: prostaglandin E1 receptor; EP2: prostaglandin E2 receptor; EP3: prostaglandin E3 receptor; EP4: prostaglandin E4 receptor.
Cong Wu, Yanjuan Zhu, Changpeng Xie, Haobo Liu, Yuanming Pan, Chang'e Liu   +5 more
wiley   +1 more source

Proteomic Diversity of the Sea Anemone <i>Actinia fragacea</i>: Comparative Analysis of Nematocyst Venom, Mucus, and Tissue-Specific Profiles. [PDF]

Mar Drugs
Barroso RA, Rodrigues T, Campos A, Almeida D, Guardiola FA, Turkina MV, Antunes A.   +6 more
europepmc   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source