Results 71 to 80 of about 28,630 (299)

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Preliminary analysis of the proteolytic enzymes in the excretory-secretory products of the adult stages of the dog hookworm Uncinaria stenocephala

open access: yesParasite, 2001
The paper describes an introductory characterisation of proteinases present in the excretory-secretory products (ESP) of adult Uncinaria stenocephala.
Kotomski G., Wedrychowicz H.
doaj   +1 more source

Ethylene Signaling Mediates a Maize Defense Response to Insect Herbivory

open access: yesMolecular Plant-Microbe Interactions, 2006
The signaling pathways that enable plants to mount defenses against insect herbivores are known to be complex. It was previously demonstrated that the insect-resistant maize (Zea mays L.) genotype Mp708 accumulates a unique defense cysteine proteinase ...
Antoine L. Harfouche   +4 more
doaj   +1 more source

Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability. [PDF]

open access: yesPLoS Pathogens, 2016
Dengue is the most prevalent arboviral disease in humans and a major public health problem worldwide. Systemic plasma leakage, leading to hypovolemic shock and potentially fatal complications, is a critical determinant of dengue severity.
Henry Puerta-Guardo   +2 more
doaj   +1 more source

Investigação sobre a adaptação do inseto praga de cereais Tenebrio molitor a inibidores de proteinases digestivas [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2010Nas larvas de Tenebrio molitor (verme do trigo) são encontrados variados tipos de proteinases ...
Alexandre, Daniel
core  

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

open access: yesAdvanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig   +3 more
wiley   +1 more source

The early history of intracellular cysteine proteinase inhibitors

open access: yesFrontiers in Bioscience, 2010
Scientists at the beginning of their careers often rely on the information obtained from review articles. Furthermore, the review articles are commonly used by sponsors in making their funding decisions of scientific projects. Thus it is very important to give a balanced view of the past as well as the present of the field discussed in those papers. In
openaire   +2 more sources

Cystatin C: Its role in pathogenesis of OSMF

open access: yesJournal of Oral Biology and Craniofacial Research, 2014
Oral Submucous Fibrosis (OSF) is a chronic disorder characterized by fibrosis of the mucosa lining the upper digestive tract involving the oral cavity, oro- and hypopharynx and the upper third of the oesophagus.
P.C. Anila Namboodiripad
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Cystatin C based peptidyl diazomethanes as cysteine proteinase inhibitors: Influence of the peptidyl chain length

open access: yes, 1992
The peptidyl diazomethanes Cbz-Gly-CHN2, Boc-Val-Gly-CHN2, H-Leu-Val-Gly-CHN2, Cbz-Leu-Val-Gly-CHN2 and Cbz-Arg-Leu-Val-Gly-CHN2, with peptidyl portions modelled after the proposed cysteine proteinase interacting N-terminal segment of human cystatin C ...
Hall, Anders   +6 more
core   +1 more source

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