Results 11 to 20 of about 47,323 (291)
Urolithiasis in dogs: Evaluation of trends in urolith composition and risk factors (2006‐2018)
Journal of Veterinary Internal Medicine, 2021 Background Urolithiasis is a common and often recurrent problem in dogs. Objective To evaluate trends in urolith composition in dogs and to assess risk factors for urolithiasis, including age, breed, sex, neuter status, urolith location, and bacterial ...
Lucy Kopecny +3 more
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Intracellular Distribution of Cystine in Cystine-Loaded Proximal Tubules [PDF]
Pediatric Research, 1994 Cellular cystine loading with cystine dimethyl ester has been shown to inhibit transport in proximal convoluted tubules perfused in vitro and decrease the rate of oxygen consumption in suspensions of proximal tubules. The present study was designed to examine the intracellular distribution of cystine in this model of the Fanconi syndrome of cystinosis ...
Michel Baum +2 more
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Biomarkers in Nephropathic Cystinosis: Current and Future Perspectives
Cells, 2022 Early diagnosis and effective therapy are essential for improving the overall prognosis and quality of life of patients with nephropathic cystinosis. The severity of kidney dysfunction and the multi-organ involvement as a consequence of the increased ...
Francesco Emma +9 more
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A mTORC1-mediated cyst(e)ine sensing mechanism governing GPX4 synthesis and ferroptosis
Molecular & Cellular Oncology, 2021 Ferroptosis is a cell death mechanism triggered by lipid peroxidation. Our recent study linked cyst(e)ine availability with glutathione peroxidase 4 (GPX4) protein synthesis and ferroptosis mitigation via a Rag-mechanistic target of rapamycin complex 1 ...
Yuelong Yan, Guang Lei, Boyi Gan
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Chronic Sulfasalazine Treatment in Mice Induces System xc− - Independent Adverse Effects
Frontiers in Pharmacology, 2021 Despite ample evidence for the therapeutic potential of inhibition of the cystine/glutamate antiporter system xc− in neurological disorders and in cancer, none of the proposed inhibitors is selective. In this context, a lot of research has been performed
Lise Verbruggen +10 more
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PAMJ Clinical Medicine, 2020 Nous rapportons le cas d'un patient de 55 ans, sans antécédents pathologiques notables, qui consulte pour baisse d`acuité visuelle d'installation progressive.
Narjisse Taouri, Wafae Cherkaoui
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Life, 2022 The plant Saussurea costus (Falc) Lipsch has many biological activities and a strong curative and preventive power against a variety of diseases including cancer, diabetes, and hemorrhoids. In the current study, phytochemical screening was carried out as
Naima Mammate +8 more
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Antioxidants, 2018 Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell.
Rodolfo Sumayao +2 more
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Ciência Rural, 1999 No Brasil, o abate de suínos machos inteiros é proibido, mas esta categoria apresenta vantagens econômicas quando comparada a suínos machos castrados. Trabalhos têm demonstrado que existem diferenças no requerimento nutricional entre essas categorias.
Cezar Dobler Castagna +3 more
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The content of non-essential amino acids in the grains of winter and spring varieties of oats (Avena sativa L.) under the conditions of Central Southern Bulgaria [PDF]
Agroznanje, 2013 The purpose of this survey is to study the content of non-essential amino acids in four winter (Dunav 1, Ruse 8, Resor 1, Line M-K) and five spring (Obraztsov chiflik 4, Mina, HiFi, Novosadski golozarnest and Prista 2) cultivars of oats grown in Central ...
Georgieva T., Zorovski P.
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