Results 21 to 30 of about 49,829 (291)

The relationship between structural lipids of sheep wool with its individual macrostructural components, chemical composition and physical indicators

open access: yesБіологія тварин, 2021
The data on the peculiarities of the structural organization, chemical composition and physical parameters of sheep wool of different breeds depending on the type of their hair are presented.
P. V. Stapay   +3 more
doaj   +1 more source

The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells

open access: yesAntioxidants, 2018
Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell.
Rodolfo Sumayao   +2 more
doaj   +1 more source

FANCONI SYNDROME SECONDARY TO CYSTINOSIS IN YOUNG MALE: A CASE REPORT

open access: yesKhyber Medical University Journal, 2021
INTRODUCTION:  Nephropathic cystinosis is a rarely occurring inherited metabolic disorder, leading to Fanconi syndrome, progressive renal failure and a range of extra-renal manifestations including endocrinopathies.
Samina Bibi   +5 more
doaj   +1 more source

Cystine Stones: Developments in Minimally Invasive Surgery and Their Impact on Morbidity and Stone Clearance

open access: yesResearch and Reports in Urology, 2023
Thomas Hughes,1 Lazaros Tzelves,2 Bhaskar K Somani3 1Department of Urology, Warwick Hospital, Warwick, UK; 2Department of Urology, Sismanogleio Hospital, National and Kapodistrian University of Athens, Athens, Greece; 3Department of Urology, University ...
Hughes T, Tzelves L, Somani BK
doaj  

Antioxidant and Anti-Urolithiatic Activity of Aqueous and Ethanolic Extracts from Saussurea costus (Falc) Lispich Using Scanning Electron Microscopy

open access: yesLife, 2022
The plant Saussurea costus (Falc) Lipsch has many biological activities and a strong curative and preventive power against a variety of diseases including cancer, diabetes, and hemorrhoids. In the current study, phytochemical screening was carried out as
Naima Mammate   +8 more
doaj   +1 more source

Cystine nephrolithiasis.

open access: yesTranslational andrology and urology, 2014
Our understanding of the molecular basis of cystinuria has deepened as the result of the causative genes, SLC3A1 and SLC7A9, being identified. The proteins coded for by these genes form a heterodimer responsible for reabsorption of filtered cystine in the proximal tubule. Failure of this transport system to be targeted to the apical membrane, as in the
Fattah, Hasan   +2 more
openaire   +2 more sources

Chronic Sulfasalazine Treatment in Mice Induces System xc− - Independent Adverse Effects

open access: yesFrontiers in Pharmacology, 2021
Despite ample evidence for the therapeutic potential of inhibition of the cystine/glutamate antiporter system xc− in neurological disorders and in cancer, none of the proposed inhibitors is selective. In this context, a lot of research has been performed
Lise Verbruggen   +10 more
doaj   +1 more source

DETOXICATION OF CYANIDE BY CYSTINE

open access: yesJournal of Biological Chemistry, 1956
SUMMARY Chemical studies on the nature of the reaction product between cystine and cyanide ion support formulation of the structure as 2-imino-4-thiazoli- dinecarboxylic acid. The compound was inert metabolically when fed to the rat or when injected. On treatment with acid, a small amount of thio- cyanate was produced.
J L, WOOD, S L, COOLEY
openaire   +2 more sources

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Microwave‐Assisted Aqueous Synthesis of Gelatin‐Norbornene for Hydrogel Crosslinking and Bioprinting

open access: yesAdvanced Materials Technologies, EarlyView.
A microwave‐assisted reaction is utilized to synthesize gelatin‐norbornene (GelNB), achieving a high degree of norbornene functionalization while reducing the macromer's upper critical solution temperature. The resulting GelNB macromer has high solubility at room temperature, facilitating light‐based 3‐dimensional (3D) printing of thiol‐norbornene ...
Jonathan B. Bryan, Chien‐Chi Lin
wiley   +1 more source

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