Results 51 to 60 of about 109,679 (389)
Cystine plug and other novel mechanisms of large mechanical stability in dimeric proteins [PDF]
We identify three dimeric proteins whose mechanostability is anisotropic and should exceed 1 nN along some directions. They come with distinct mechanical clamps: shear-based, involving a cystine slipknot, and due to dragging of a cystine plug through a cystine ring.
arxiv +1 more source
Cancer cells develop multiple strategies to evade T cell-mediated killing. On one hand, cancer cells may preferentially rely on certain amino acids for rapid growth and metastasis.
Chenfeng Han+12 more
semanticscholar +1 more source
Cysteine, Glutathione, and Thiol Redox Balance in Astrocytes
This review discusses the current understanding of cysteine and glutathione redox balance in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte activation on pathways that provide cysteine as a precursor for ...
Gethin J. McBean
doaj +1 more source
Evaluation and medical management of patients with cystine nephrolithiasis: a consensus statement.
PURPOSE Cystinuria is a genetic disorder with both autosomal recessive or incompletely dominant inheritance. The disorder disrupts cystine and other dibasic amino acid transport in the proximal tubules of the kidney resulting in recurrent kidney stone ...
B. Eisner+11 more
semanticscholar +1 more source
FANCONI SYNDROME SECONDARY TO CYSTINOSIS IN YOUNG MALE: A CASE REPORT
INTRODUCTION: Nephropathic cystinosis is a rarely occurring inherited metabolic disorder, leading to Fanconi syndrome, progressive renal failure and a range of extra-renal manifestations including endocrinopathies.
Samina Bibi+5 more
doaj +1 more source
The data on the peculiarities of the structural organization, chemical composition and physical parameters of sheep wool of different breeds depending on the type of their hair are presented.
P. V. Stapay+3 more
doaj +1 more source
Influence of Sulfur-Containing Diamino Acid Structure on Covalently Crosslinked Copolypeptide Hydrogels. [PDF]
Biologically occurring non-canonical di-α-amino acids were converted into new di-N-carboxyanhydride (di-NCA) monomers in reasonable yields with high purity.
Deming, Timothy J+4 more
core +1 more source
Our understanding of the molecular basis of cystinuria has deepened as the result of the causative genes, SLC3A1 and SLC7A9, being identified. The proteins coded for by these genes form a heterodimer responsible for reabsorption of filtered cystine in the proximal tubule. Failure of this transport system to be targeted to the apical membrane, as in the
Fattah, Hasan+2 more
openaire +2 more sources
Crystallization of cystine [PDF]
Cystine is an amino acid, which is a constituent of the urinary stones. It also is deposited in eyes, thyroid glands, bone marrow and white blood corpuscles. Crystals of cystine have been grown by both solution and gel methods. Small bunched hexagonal crystals, along with many other morphological crystals of size 0.3 mm across, were obtained.
E.K. Girija+2 more
openaire +1 more source