Molecular jamming - the cystine slipknot mechanical clamp in all-atom simulations
A recent survey of 17 134 proteins has identified a new class of proteins which are expected to yield stretching induced force-peaks in the range of 1 nN. Such high force peaks should be due to forcing of a slip-loop through a cystine ring, i.e.
Carrion-Vazquez M. +4 more
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The effect of pressure on the crystal structure of hexagonal L-cystine [PDF]
The crystal structure of hexagonal L-cystine has been determined at room temperature at pressures between 0.4 and 3.7 GPa; unit-cell dimensions were measured up to 6.4 GPa. The structure of this phase consists of molecules in their zwitterionic form, and
Allan, D R +4 more
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Scaffolding of Cystine‐Stabilized Miniproteins
AbstractBiomolecular scaffolds were engineered by genetically fusing robust miniproteins in a sequence, like a chain. By fusing these miniprotein chains to a teal fluorescent protein (TFP), an efficient strategy was devised for their production in E. coli.
Arjan Barendregt +7 more
openaire +4 more sources
Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking. [PDF]
Tunneling nanotubes (TNTs) are cellular extensions enabling cytosol-to-cytosol intercellular interaction between numerous cell types including macrophages.
Cherqui, Stephanie +4 more
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The electrophoresis of transferrins in urea/polyacrylamide gels [PDF]
The denaturation of transferrin by urea has been studied by (a) electrophoresis in polyacrylamide gels incorporating a urea gradient, (b) measurements of the loss in iron-binding capacity and (c) u.v. difference spectrometry. In human serum transferrin
Evans, RW, Williams, J
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Lysine and methionine + cystine for laying hens during the post-molting phase
One experiment was conducted to evaluate the effect of using different lysine and methionine + cystine levels on body weight recovery, performance, and egg quality of laying hens during the post-molting period.
C H de F Domingues +7 more
doaj +1 more source
Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. [PDF]
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as
Brewer, Gregory J +3 more
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Effect of cystine loading and cystine dimethylester on renal brushborder membrane transport
The effect of loading renal tubule cells with cystine was studied by incubating them with cystine dimethylester. Proline uptake into brushborder membrane vesicles isolated from the cystine loaded cells was not different from that observed into brushborder vesicles isolated from tubules incubated in buffer alone.
John W. Foreman, Linda L. Benson
openaire +3 more sources
Organic Fodder Production in Intensive Organic Livestock Production in Europe: Recent Scientific Findings and the Impact on the Development of Organic Farming [PDF]
Organic farming is practiced in over 100 countries on more than 26 million hectares. In the European Union (EU 25), about 5.6 million hectares of farm land are certified under the EU organic farming regulation 2092/91/EEC.
Böhm, Herwart, Rahmann, Gerold
core
The chalcogen elements oxygen, sulfur, and selenium are essential constituents of side chain functions of natural amino acids. Conversely, no structural and biological function has been discovered so far for the heavier and more metallic tellurium ...
Agh R +13 more
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