Results 161 to 170 of about 79,534 (186)
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A ribozyme that lacks cytidine
Nature, 1999The RNA-world hypothesis proposes that, before the advent of DNA and protein, life was based on RNA, with RNA serving as both the repository of genetic information and the chief agent of catalytic function. An argument against an RNA world is that the components of RNA lack the chemical diversity necessary to sustain life.
J, Rogers, G F, Joyce
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Fluorescent adenosine and cytidine derivatives
Biochemical and Biophysical Research Communications, 1972Summary The reaction of chloroacetaldehyde with adenosine and cytidine produces a fluorescent product in each case. These products are easily distinguishable spectroscopically by their fluorescence emission maxima. Since the reaction is carried out in aqueous media under mild conditions of pH and temperature, it should prove extremely useful in ...
J R, Barrio, J A, Secrist, N J, Leonard
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Carbohydrate Research, 1984
Abstract A practical, seven-step synthesis of 5-(β- d -ribofuranosyl)cytosine ( 1 , ψ-cytidine) was achieved. ψ-Uridine was converted into the 2′,3′-isopropylidene acetal 2 in 85% yield. Tosylation of 2 to the 5′-sulfonate 3 , followed by deacetonation, afforded 5′- O -tosyl-ψ-uridine ( 6 ) in good yield.
K W, Pankiewicz +3 more
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Abstract A practical, seven-step synthesis of 5-(β- d -ribofuranosyl)cytosine ( 1 , ψ-cytidine) was achieved. ψ-Uridine was converted into the 2′,3′-isopropylidene acetal 2 in 85% yield. Tosylation of 2 to the 5′-sulfonate 3 , followed by deacetonation, afforded 5′- O -tosyl-ψ-uridine ( 6 ) in good yield.
K W, Pankiewicz +3 more
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An Overview of Cytidine Deaminases
International Journal of Hematology, 2006Enzymes that deaminate cytidine to uridine play an important role in a variety of pathways from bacteria to man. Ancestral members of this family were able to deaminate cytidine only in a mononucleotide or nucleoside context. Recently, a family of enzymes has been discovered with the ability to deaminate cytidines on RNA or DNA.
Naveenan, Navaratnam, Rizwan, Sarwar
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Acta Crystallographica Section C Crystal Structure Communications, 1993
β-Cytidine exhibits extensive three-dimensional hydrogen-bonding interactions in its crystal structure; every H atom bonded to an N or O atom (five in total) is involved and each β-cytidine molecule contributes to ten intermolecular hydrogen bonds. The O...O and O...N distances range from 2.707 (4) to 2.947 (4) A.
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β-Cytidine exhibits extensive three-dimensional hydrogen-bonding interactions in its crystal structure; every H atom bonded to an N or O atom (five in total) is involved and each β-cytidine molecule contributes to ten intermolecular hydrogen bonds. The O...O and O...N distances range from 2.707 (4) to 2.947 (4) A.
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Wasserstoffbrücken in Cytidin⋅⋅⋅H+⋅⋅⋅Cytidin‐DNA‐Basenpaaren
Angewandte Chemie, 2012Anna Lena Lieblein +4 more
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Cyclopentenyl cytidine analogue
Biochemical Pharmacology, 1985Robert I. Glazer +3 more
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