Results 71 to 80 of about 79,534 (186)

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

open access: yes, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna   +6 more
core   +2 more sources

Effect of Human MTHFR Gene Polymorphisms in Morbidly Obese Population on Elevate Risk of Type 2 Diabetes

open access: yesNano Biomedicine and Engineering, 2018
In this paper, based on the association of methylenetetrahydrofolate reductase (MTHFR) with type 2 diabetes (T2D), we evaluated the association of polymorphism with morbidly obesity on risk type 2 diabetes.
Fatimah Sahib Abed   +4 more
doaj   +1 more source

Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells. [PDF]

open access: yes, 2017
Renal cell carcinoma (RCC) is a deadly malignancy due to its tendency to metastasize and resistance to chemotherapy. Stem-like tumor cells often confer these aggressive behaviors.
Dai, Jin   +10 more
core   +3 more sources

Incorporation of tritiated cytidine into ribonucleic acid by isolated pea nuclei [PDF]

open access: yes, 1962
A new method for the isolation of the nuclei from plant tissue has been devised. This method consists in passing the plant tissue through a set of spring-loaded, counter-rotating rollers and collecting the liberated nuclei in sucrose solution containing ...
Chipchase, Margaret I., Rho, Joon H.
core   +1 more source

細胞プロファイリングシステムを用いた細胞、組織製品の特性解析 [PDF]

open access: yes, 2019
博士(医学) 甲第687号(主論文の要旨、要約、審査結果の要旨、本文),著者名:Ayako Tominaga・Masato Sato・Takumi Takahashi・Eriko Toyoda・Kenichi Toyoda・Takashi Suzuki・Masatoshi Takahashi・Masahiko Watanabe・Ken Okazaki,タイトル:Quality assessment of cellular and tissue-based products using liquid ...
冨永 絢子
core   +2 more sources

Orotic Aciduria [PDF]

open access: yes, 2018
Orotic acid is an intermediate found in the pathway for pyrimidine synthesis. The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) catalyzes the production of orotic acid by the conversion of the compound dihydroorotate to orotic acid.
Fonteh, Aliah L
core   +1 more source

Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report

open access: yesBMC Cancer, 2020
Background Pancreatic adenosquamous carcinoma has a poor prognosis, with limited prospective trial data to guide optimal treatment. The potential impact of drug metabolism on the treatment response of patients with pancreatic adenosquamous carcinoma is ...
Claire M. Connell   +8 more
doaj   +1 more source

Interaction of Nucleosides and Related Compounds with Nucleic Acids as Indicated by the Change of Helix-Coil Transition Temperature [PDF]

open access: yes, 1962
A series of compounds has been tested for effectiveness in lowering the melting temperature of poly A and of thymus DNA. The order of increasing activity was found to be: adonitol, methyl riboside (both negligible) < cyclohexanol < phenol, pyrimidine ...
Helmkamp, G. K.   +2 more
core   +1 more source

Effect of preparation procedures on intensity of radioautographic labeling is studied [PDF]

open access: yes, 1967
Effects of tissue preparation and extractive procedures on the intensity of radioautographic labeling are presented in terms of mean grain count per cell in cells labeled with tritiated precursors of proteins or nucleic acids.
Baserga, R., Kisieleski, W. E.
core   +1 more source

Rejuvenation by cell reprogramming: A new horizon in gerontology [PDF]

open access: yes, 2018
The discovery of animal cloning and subsequent development of cell reprogramming technology were quantum leaps as they led to the achievement of rejuvenation by cell reprogramming and the emerging view that aging is a reversible epigenetic process. Here,
Brown, Oscar Alfredo   +5 more
core   +2 more sources

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