Life, 2021 Human receptor gC1qR is a 32 kD protein that mediates the cytoadherence of Plasmodium falciparum-infected erythrocytes (IEs) to human brain microvascular endothelial cells (HBMEC) and platelets.
Rowaida Bakri +3 more
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Distinct features of the host-parasite interactions between nonadherent and adherent Trichomonas vaginalis isolates. [PDF]
PLoS Neglected Tropical Diseases, 2023 Cytoadherence of Trichomonas vaginalis to human vaginal epithelial cells (hVECs) was previously shown to involve surface lipoglycans and several reputed adhesins on the parasite.
Hong-Ming Hsu +10 more
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In Silico Prediction of Plasmodium falciparum Cytoadherence Inhibitors That Disrupt Interaction between gC1qR-DBLβ12 Complex. [PDF]
Pharmaceuticals (Basel), 2022 Malaria causes about half a million deaths per year, mainly in children below 5 years of age. Cytoadherence of Plasmodium falciparum infected erythrocytes in brain and placenta has been linked to severe malaria and malarial related deaths.
Hafiz A +5 more
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Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes. [PDF]
PLoS ONE, 2017 In severe falciparum malaria cytoadherence of parasitised red blood cells (PRBCs) to vascular endothelium (causing sequestration) and to uninfected red cells (causing rosette formation) contribute to microcirculatory flow obstruction in vital organs ...
Somporn Saiwaew +18 more
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Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture. [PDF]
PLoS ONE, 2023 The human malaria parasite Plasmodium falciparum is responsible for the majority of mortality and morbidity caused by malaria infection and differs from other human malaria species in the degree of accumulation of parasite-infected red blood cells in the
Basim Othman +12 more
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An Atypical F-Actin Capping Protein Modulates Cytoskeleton Behaviors Crucial for Trichomonas vaginalis Colonization [PDF]
Microbiology Spectrum, 2023 Cytoadherence and migration are crucial for pathogens to establish colonization in the host. In contrast to a nonadherent isolate of Trichomonas vaginalis, an adherent one expresses more actin-related machinery proteins with more active flagellate ...
Kai-Hsuan Wang +8 more
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A preliminary study of the immunogenic response of plant-derived multi-epitopic peptide vaccine candidate of Mycoplasma gallisepticum in chickens [PDF]
Frontiers in Plant Science, 2023 Mycoplasma gallisepticum (MG) is responsible for chronic respiratory disease in avian species, characterized by symptoms like respiratory rales and coughing. Existing vaccines for MG have limited efficacy and require multiple doses.
Susithra Priyadarhni Mugunthan +4 more
doaj +2 more sources
The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 M5717 is a promising antimalarial drug under development that acts against multiple stages of the life cycle of Plasmodium parasites by inhibiting the translation elongation factor 2 (PfeEF2), thereby preventing protein synthesis.
Molly Parkyn Schneider +11 more
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Advanced Science, 2022 Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature.
Oscar Bate Akide Ndunge +2 more
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The bacterial protein CNF1 as a new strategy against Plasmodium falciparum cytoadherence.
PLoS ONE, 2019 Plasmodium falciparum severe malaria causes more than 400,000 deaths every year. One feature of P. falciparum-parasitized erythrocytes (pRBC) leading to cerebral malaria (CM), the most dangerous form of severe malaria, is cytoadherence to endothelium and
Valeria Messina +9 more
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