Results 21 to 30 of about 6,252 (195)

Cytoadherence characteristics of rosette-forming Plasmodium falciparum [PDF]

Infection and Immunity, 1992
Sequestration of Plasmodium falciparum-infected erythrocytes to the capillary endothelium can cause obstruction and localized tissue damage. Occlusion of vessels in falciparum malaria infection has been related to two properties of the parasite: adhesion to endothelial cells and rosette formation. Our study on P.
R, Udomsangpetch, H K, Webster, K, Pattanapanyasat, S, Pitchayangkul, S, Thaithong   +4 more
openaire   +2 more sources

Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models

Advanced Science, 2022
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature.
Oscar Bate Akide Ndunge, Nicole Kilian, Mootaz M. Salman   +2 more
doaj   +1 more source

Response : Malaria Red Cell Cytoadherence [PDF]

Science, 1989
Discussion sur les methodes utilisees pour l'etude de la cytoadherence des erythrocytes infectes par Plasmodium falciparum. Certains auteurs preconisent la methode par perfusion ex vivo de la microcirculation du mesentere de rat qui permet la detection de l'adherence a l'endothelium des veinules et se rapproche des conditions ...
C. F. OCKENHOUSE, N. N. TANDON, C. MAGOWAN, G. A. JAMIESON, J. D. CHULAY   +4 more
openaire   +1 more source

Pathogenesis of cerebral malaria—inflammation and cytoadherence [PDF]

Frontiers in Cellular and Infection Microbiology, 2014
Malgré des décennies de recherche sur le paludisme cérébral (MC), il existe encore un manque de connaissances sur les causes réelles de la MC et sur les raisons pour lesquelles certaines personnes la développent. Bien que la séquestration des globules rouges infectés par P.
Janet Storm, Alister G. Craig
openaire   +3 more sources

Inhibition of endothelial activation: A new way to treat cerebral malaria? [PDF]

, 2005
Background: Malaria is still a major public health problem, partly because the pathogenesis of its major complication, cerebral malaria (CM), remains incompletely understood.
Cianciolo, GJ, Combes, V, Grau, GE, Wassmer, SC   +3 more
core   +5 more sources

Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes. [PDF]

PLoS ONE, 2017
In severe falciparum malaria cytoadherence of parasitised red blood cells (PRBCs) to vascular endothelium (causing sequestration) and to uninfected red cells (causing rosette formation) contribute to microcirculatory flow obstruction in vital organs ...
Somporn Saiwaew, Juntima Sritabal, Nattaporn Piaraksa, Srisuda Keayarsa, Ronnatrai Ruengweerayut, Chirapong Utaisin, Patima Sila, Rangsan Niramis, Rachanee Udomsangpetch, Prakaykaew Charunwatthana, Emsri Pongponratn, Sasithon Pukrittayakamee, Anna M Leitgeb, Mats Wahlgren, Sue J Lee, Nicholas P J Day, Nicholas J White, Arjen M Dondorp, Kesinee Chotivanich   +18 more
doaj   +1 more source

Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies [PDF]

, 2006
Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA ...
Ahmed Raza, Atalay, Baruch, Baruch, Buffet, Chen, Chen, Chitnis, Cohen, Cooke, Craig, Creasey, Fagan, Flick, Fried, Gamain, Gamain, Gardner, Guyatt, J. Alexandra Rowe, Jean-Philippe Semblat, Kyes, Kyes, Langone, Lin, Mayor, Medina, Medina, Rowe, Rowe, Rowe, Salanti, Salanti, Scholander, Smith, Smith, Su, Sue A. Kyes   +37 more
core   +1 more source

Variation in the cytoadherence characteristics of malaria parasites: is this a true virulence factor?

Memorias do Instituto Oswaldo Cruz, 1992
The sequestration of Plasmodium falciparum-infected erythrocytes to the endothelial cells of brain capillaries is believed to represent one of the determining factors in the pathogenesis of cerebral malaria.
J. D. Goldring, M. Hommel
doaj   +1 more source

Automated counting for Plasmodium falciparum cytoadherence experiments [PDF]

Malaria Journal, 2011
AbstractBackgroundThe ability of mature forms ofPlasmodium falciparuminfected erythrocytes to bind to a range of host receptors including those displayed on endothelial cells has been associated with the pathology of this infection. Investigations into this adhesive phenomenon have used protein and cell-based adhesion assays to quantify the ability of ...
Mustaffa Khairul MF, Faragher Brian, Paton Douglas, Szestak Tadge, Barrett Steve D, Craig Alister G   +5 more
openaire   +4 more sources

Recent advances in malaria genomics and epigenomics [PDF]

, 2016
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian, Power, B. Joanne, Waters, Andrew P.   +2 more
core   +1 more source