Results 81 to 90 of about 46,080 (279)
A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. [PDF]
Elevated glucose consumption is fundamental to cancer, but selectively targeting this pathway is challenging. We develop a high-throughput assay for measuring glucose consumption and use it to screen non-small-cell lung cancer cell lines against ...
Chen, Bao Ying +5 more
core +1 more source
A study on the nuclear extrusion of mammalian erythroblast [PDF]
A study was carried out to clarify the mechanism of nuclear extrusion of mammalian erythroid cells by observing erythroblasts of rabbit under various conditions in vitro.
Mori, Masaharu
core +1 more source
Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochore‐associated factor.
Franziska Hentzschel +2 more
wiley +1 more source
Complex Influence of Cytochalasin B on Actin Polymerization
Abstract In the presence of very low concentrations (about 2 x 10-7 ᴍ) of cytochalasin B (CB) the time course of actin polymerization is much more sigmoidal when followed by viscosity measurements than when followed by light scattering measurements.
Dancker, P., Löw, I.
openaire +3 more sources
Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook +2 more
wiley +1 more source
Patrícia Paiva-Lima,1 Rafael M Rezende,1 Rômulo Leite,2 Igor DG Duarte,1 YS Bakhle,3 Janetti N Francischi11Department of Pharmacology, Laboratory of Inflammation and Pain, Biological Sciences Institute, Federal University of Minas ...
Paiva-Lima P +5 more
doaj
Background Somatic cell nuclear transfer in cats offers a useful tool for the generation of valuable research models. However, low birth rates after nuclear transfer hamper exploitation of the full potential of the technology.
Herrick Jason R +4 more
doaj +1 more source
Regulation of elastase and plasminogen activator secretion in resident and inflammatory macrophages by receptors for the Fc domain of immunoglobulin G. [PDF]
We have determined that the interaction of IgG-coated erythrocytes (EIgG) and complement-coated erythrocytes (EIgMC) with macrophage Fc and complement receptors, respectively, modulates the secretion of the neutral proteinases, elastase, and plasminogen ...
Takemura, R, Werb, Z
core
Compartmentalisation and localisation of the translation initiation factor (eIF) 4F complex in normally growing fibroblasts [PDF]
Previous observations of association of mRNAs and ribosomes with subcellular structures highlight the importance of localised translation. However, little is known regarding associations between eukaryotic translation initiation factors and cellular ...
Barbarese +82 more
core +1 more source

