An enantioselective, modular, and general route to the cytochalasins: Synthesis of L-696,474 and cytochalasin B [PDF]
The cytochalasins are structurally complex natural products with a broad range of apparently unrelated effects in different biological systems. Different members of the family have variously demonstrated inhibitory activity toward the formation of actin filaments, toward the functioning of HIV protease, and toward the process of angiogenesis.
Andrew G. Myers, Andrew M. Haidle
openaire +4 more sources
The chemistry and some biological effects of the cytochalasins [PDF]
W B Turner, S B Carter
openaire +4 more sources
New polyketides from the liquid culture of Diaporthe breyniae sp. nov. (Diaporthales, Diaporthaceae) [PDF]
During the course of a study on the biodiversity of endophytes from Cameroon, a fungal strain was isolated. A multigene phylogenetic inference using five DNA loci revealed that this strain represents an undescribed species of Diaporthe, which is ...
Blondelle Matio Kemkuignou+6 more
doaj +3 more sources
Two new cytochalasins from the endophytic fungus Xylaria sp. GDGJ-77B
Two new open-chain cytochalasins, xylarchalasins A and B (1 and 2), together with six known analogues (3-8), were isolated from the endophytic fungus Xylaria sp. GDGJ-77B from the Chinese medicinal plant Sophora tonkinensis.
Zhaolong Xu+6 more
semanticscholar +1 more source
Cryptococcus neoformans is an important human pathogen with limited options for treatments. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth inhibition, differential ...
Bruno Perlatti+6 more
doaj +1 more source
An NMR Analysis of 10-Indol Cytochalasin Chaetoglobosin F
Cytochalasins are a group of natural products from fungus, and have been attracting lots of research interests in the field of microbiology. Cytochalasins possess complex and diverse structures, making nuclear magnetic resonance (NMR) based structure ...
YIN Tian-peng+5 more
doaj +1 more source
Diversified Chaetoglobosins from the Marine-Derived Fungus Emericellopsis sp. SCSIO41202
Two undescribed cytochalasins, emeriglobosins A (1) and B (2), together with nine previously reported analogues (3–11) and two known tetramic acid derivatives (12, 13) were isolated from the solid culture of Emericellopsis sp. SCSIO41202.
Surun Shao+9 more
doaj +1 more source
Diversely Functionalised Cytochalasins through Mutasynthesis and Semi‐Synthesis
Mutasynthesis of pyrichalasin H from Magnaporthe grisea NI980 yielded a series of unprecedented 4′‐substituted cytochalasin analogues in titres as high as the wild‐type system (≈60 mg L−1).
Chongqing Wang+9 more
semanticscholar +1 more source
A new species of Daldinia (Xylariaceae) from the Argentine subtropical montane forest [PDF]
Based on a combination of morphological, molecular phylogenetic and chemotaxonomic evidence, a new species of Daldinia from Northwest of Argentina is described. Daldinia korfii is morphologically related to D.
Hladki, Adriana Ines+5 more
core +1 more source
Comparative two-dimensional gel analysis and microsequencing identifies gelsolin as one of the most prominent downregulated markers of transformed human fibroblast and epithelial cells [PDF]
A systematic comparison of the protein synthesis patterns of cultured normal and transformed human fibroblasts and epithelial cells, using two-dimensional gel protein analysis combined with computerized imaging and data acquisition, identified a 90-kD ...
Bauw, Guy+4 more
core +1 more source