Results 111 to 120 of about 460,654 (283)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Inhibitory Effect of Lygodium Root on the Cytochrome P450 3A Enzyme in vitro and in vivo

Drug Design, Development and Therapy, 2020
Yunfang Zhou,1,* Ailian Hua,2,* Quan Zhou,1 Peiwu Geng,1 Feifei Chen,1 Lianhe Yan,1 Shuanghu Wang,1 Congcong Wen3 1The Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People’s Hospital of Lishui ...
Zhou Y, Hua A, Zhou Q, Geng P, Chen F, Yan L, Wang S, Wen C   +7 more
doaj  

Synthesis and the effect of a novel benzoxazole compound on breast cancer cell line

Medicine Science, 2019
Breast cancer today is the most frequent cancer among women, and the second most common cause of cancer deaths among women. The aim of this study was to synthesize a new benzoxazole derivative, scan it for anti-cancer potential by MTT test using ...
Funda Kosova, Ozlem Temiz Arpaci, Ercument Olmez, Ibrahim Tuglu   +3 more
doaj   +1 more source

Smart Hydrogel Doped by Metal–Organic Frameworks for Renewable Self‐Pumping Enzymatic Reactors

Advanced Science, EarlyView.
Renewable self‐pumping enzymatic reactors based on thermo‐stimulated cyclic contraction/expansion of metal‐organic frameworks‐doped hydrogel. Abstract The construction of high‐performance immobilized enzymes is vastly desired for green biotransformation.
Yuxi Zhu, Shenghao Wang, Yueyuan Luo, Linbo Cao, Xiuxiu Guo, Yue Zhang, Mingmin Li, Tie Wang   +7 more
wiley   +1 more source

Piperine as an Herbal Alternative for the Prevention of Drug-Induced Liver Damage Caused by Paracetamol

Pharmaceuticals
Background/Objective: Hepatic drug intoxication is becoming increasingly common with the increasing use of chronic medications. Piperine has emerged as a promising alternative for protecting the liver against drug-induced injury.
Aline Meireles Coelho, Isabela Ferreira Queiroz, Luiza Oliveira Perucci, Tatiana Prata Menezes, Wanderson Geraldo Lima, André Talvani, Daniela Caldeira Costa   +6 more
doaj   +1 more source

Phylogenetic relationships among several freshwater fishes (Family: Cyprinidae) in Malaysia inferred from partial sequencing of the Cytochrome b mitochondrial DNA (mtDNA) gene [PDF]

, 2012
The phylogenetic relationships among 23 species of Malaysian freshwater fishes in the family Cyprinidae was inferred by partial sequencing of the Cytochrome b (Cyt b) mitochondrial gene.
Abdul Rahim, Khairul Adha, Daud, Siti Khalijah, Esa, Yuzine, Japning, Jeffrine Rovie Ryan, Siraj, Siti Shapor, Stephen, Sungan, Tan, Soon Guan   +6 more
core  

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Phylogenetics, divergence and morphology of New Zealand Eleotridae (Gobiomorphus Gill) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Ecology at Massey University, Palmerston North, New Zealand [PDF]

, 2006
The genus Gobiomorphus Gill (1863) is the only representative freshwater Eleotridae in New Zealand and is comprised of seven species, of which four are diadromous.
Atkinson, Emily
core  

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

In situ spectroscopy reveals that microorganisms in different phyla use different electron transfer biomolecules to respire aerobically on soluble iron

Frontiers in Microbiology, 2016
Absorbance spectra were collected on twelve different live microorganisms, representing six phyla, as they respired aerobically on soluble iron at pH 1.5.
Robert Blake, Micah D. Anthony, Jordan D. Bates, Theresa Hudson, Kamilya M. Hunter, Brionna J. King, Bria L. Landry, Megan L. Lewis, Richard G. Painter   +8 more
doaj   +1 more source