Results 201 to 210 of about 460,654 (283)

Increasing the succinate yield in Actinobacillus succinogenes by fumigation of H2 in a bioreactor

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The microbial conversion of CO2 into value‐added chemicals offers a promising and scalable route for sustainable bioproduction, particularly under mild reaction conditions and with technically straightforward reactor configurations. Actinobacillus succinogenes, a natural succinate producer, can fix CO2 through anaplerotic carboxylation but its
Julian Tix, Gustav Zimpel, Roland Ulber, Nils Tippkötter   +3 more
wiley   +1 more source

Ultrahigh Dose Rate Irradiation Regulates Mitochondrial DNA-induced Interferon-β Secretion via Cytochrome c Leakage. [PDF]

MedComm (2020)
Lv J, Sun J, Luo Y, Liu J, Wu D, Fang Y, Mourou G, Huang S, Yang G, Yan X.   +9 more
europepmc   +1 more source

Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

British Journal of Clinical Pharmacology, EarlyView.
Aim To characterize pharmacokinetic changes of sertraline and its metabolite during pregnancy and postpartum, and their relationship to maternal postpartum depressive symptoms. Methods This was a prospective observational, longitudinal study of pregnant women with a major depressive disorder treated with sertraline (N = 185 women, 205 pregnancies ...
Sílvia M. Illamola, Zachary N. Stowe, Marc L. Kalin, Michael D. Evans, Catherine M. Sherwin, Maged M. Costantine, D. Jeffrey Newport, James C. Ritchie, Angela K. Birnbaum   +8 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Protective and therapeutic effects of gallic acid on medication-related osteonecrosis of the jaw in rats: modulation of inflammation, fibrosis and endoplasmic reticulum/mitochondrial stress pathways. [PDF]

BMC Oral Health
Yazıcı T, Isleyen M, Imeci A, Asci H, Tepebasi MY, Gülal A, Kolay O, Tasan S, Karapınar SE, Ozmen O.   +9 more
europepmc   +1 more source

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

British Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog, Niven Mehra, Anouk van Kleef, Diederik M. Somford, Inge M. van Oort, Alex L. T. Imholz, Paul Hamberg, Nielka P. van Erp, Emmy Boerrigter   +8 more
wiley   +1 more source

Investigating the role of cytochrome <i>bd</i> oxidases in the antibacterial activity of madecassic acid and derivatives thereof. [PDF]

RSC Med Chem
Henry SA, Sansom GN, Tran TTP, Boughton RA, Joiner G, Webster CM, de Silva HIC, Garrett MD, Serpell CJ, Robinson GK, Shepherd M.   +10 more
europepmc   +1 more source

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert, Jenny Dimakos, Ying Cui, Kristian B. Filion, Christel Renoux, Antonios Douros   +5 more
wiley   +1 more source

The role of cytochrome bc₁ inhibitors in future tuberculosis treatment regimens. [PDF]

Nat Commun
Aguilar-Pérez C, Lenaerts AJ, Villellas C, Guillemont J, Dallow J, Painter H, Ammerman NC, Hassan A, Golovkine G, Brock L, Sordello S, Chauffour A, Aubry A, Mai TC, Wong S, Clark TG, Nam K, Kim J, Choi J, Crabbe M, Esquivias J, Lounis N, Stoops B, Amssoms K, Bartolome-Nebreda JM, Gruppo V, Robertson GT, Veziris N, Upton AM, Nuermberger EL, Cox V, Ballell L, Baeten B, Koul A, Pym AS, Wall RJ, Lamprecht DA.   +36 more
europepmc   +1 more source