Results 101 to 110 of about 19,855,151 (220)

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Exosome profile and composite indices reflect immune exhaustion in periodontitis

Scientific Reports
Introduction Exosomes are small extracellular vesicles that regulate immune responses, inflammation, and tissue homeostasis. While several exosomal molecules have been investigated individually in periodontitis, a functional characterization based on ...
Marco Bonilla, Manuel Bravo, Irene Peñalver, Francisco Mesa   +3 more
doaj   +1 more source

Multiple haem lyase genes indicate substrate specificity in cytochrome c biogenesis.

, 2006
c-Type cytochromes are a widespread class of proteins that play a vital role in the energy-conserving metabolism of prokaryotic and eukaryotic organisms.
Simon, J., Hartshorne, S., Hartshorne, R. S., Richardson, D.J., S. Hartshorne, D.J. Richardson, J. Simon, Richardson, D. J.   +7 more
core   +1 more source

Sex‐Specific Early Life Corticosterone Stress‐Coping Capacity Is Linked to Mitochondrial Content and Telomere Maintenance

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Glucocorticoids are upregulated during acute challenges, contributing to maintenance of energy balance. However, if this upregulation exceeds a threshold or becomes chronic, it can lead to harmful effects. Investigating the factors behind between‐individual variation in the magnitude of the response to acute stress and how effectively ...
Mauricio Guillen‐Parra, Alberto Velando, Bibiana Montoya, Roxana Torres   +3 more
wiley   +1 more source

Maternal Nutrient Excess Induces Stress Signaling and Decreases Mitochondrial Number in Term Fetal Baboon Skeletal Muscle

Biology
Maternal obesity programs the fetus for increased risk of chronic disease development in early life and adulthood. We hypothesized that maternal nutrient excess leads to fetal inflammation and impairs offspring skeletal muscle mitochondrial biogenesis in
Xu Yan, Carolina Tocantins, Mei-Jun Zhu, Susana P. Pereira, Min Du   +4 more
doaj   +1 more source

Assembly factors and ATP-dependent proteases in cytochrome c oxidase biogenesis

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2010
Eukaryotic cytochrome c oxidase (CcO), the terminal enzyme of the energy-transducing mitochondrial electron transport chain is a hetero-oligomeric, heme-copper oxidase complex composed of both mitochondrially and nuclear-encoded subunits. It is embedded in the inner mitochondrial membrane where it couples the transfer of electrons from reduced ...
Stiburek, Lukas, Zeman, Jiri
openaire   +2 more sources

Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6

Life Science Alliance, 2019
The structures of the mitochondrial complex IV assembly factor Coa6 and a pathogenic mutant variant (W59CCoa6) are reported, providing molecular mechanisms for its mode of action and the loss-of-function mutation.
Shadi Maghool, N Dinesha G Cooray, David A Stroud, David Aragão, Michael T Ryan, Megan J Maher   +5 more
doaj   +1 more source

A periplasmic and extracellular c-type cytochrome of Geobacter sulfurreducens acts as a ferric iron reductase and as an electron carrier to other acceptors or to partner bacteria [PDF]

, 1998
An extracellular electron carrier excreted into the growth medium by cells of Geobacter sulfurreducens was identified as a c-type cytochrome. The cytochrome was found to be distributed in about equal amounts in the membrane fraction, the periplasmic ...
Schink, B., Schink, Bernhard, Cord-Ruwisch, R., Seeliger, Sabine, Cord-Ruwisch, Ralf, Seeliger, S.   +5 more
core  

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Mutant CHCHD10 disrupts cytochrome c oxidation and activates mitochondrial retrograde signaling

EMBO Molecular Medicine
Mutations in CHCHD10, a mitochondrial intermembrane space (IMS) protein implicated in proteostasis and cristae maintenance, cause mitochondrial disease. Knock-in mice modeling the human CHCHD10 S59L variant associated with ALS–FTD develop a mitochondrial
Márcio Augusto Campos-Ribeiro, Erminia Donnarumma, Hendrik Nolte, Paul Cobine, Elodie Vimont, Dusanka Milenkovic, Juan Diego Hernandez-Camacho, Francina Langa-Vives, Etienne Kornobis, Esthel Pénard, Sonny Yde, Thomas Langer, Véronique Paquis-Flucklinger, Timothy Wai   +13 more
doaj   +1 more source