Results 171 to 180 of about 242,283 (275)

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

<i>m</i>RNA Expression of Two Colon Enzymes in Pre-Pubertal Gilts During a 42-Day Exposure to Zearalenone. [PDF]

Toxins (Basel)
Gajęcka M, Zielonka Ł, Gajęcki MT.
europepmc   +1 more source

Metal‐Mediated Protein Engineering within Live Cells

Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.
This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley   +1 more source

Biochar in the circular bioeconomy: a bibliometric analysis of technologies, applications, and trends

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biochar has attracted considerable attention in recent years for its wide‐ranging applications, particularly its role in carbon sequestration as a strategy to mitigate greenhouse gas emissions. Its emerging uses within the circular bioeconomy also position it as a valuable tool for environmental management, and ongoing research continues to ...
Jean Agustin Velasquez‐Pinas, Parisa Ghofrani‐Isfahani, Diego Yepes Maya, Giulia Ravenni, Luiz Eduardo Nochi Castro, Irini Angelidaki, Tânia Forster‐Carneiro   +6 more
wiley   +1 more source

Nitrite Reductases in Biomedicine: From Natural Enzymes to Artificial Mimics. [PDF]

Research (Wash D C)
Zhu S, Liu Z, Hu B, Feng Y, Pan G.
europepmc   +1 more source

Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is extensively metabolized via cytochrome P450 (CYP) enzymes, predominantly CYP2C19 and CYP3A4. Drugs influencing the activity or expression of CYP enzymes can cause clinically relevant changes in the metabolism and voriconazole exposure. Metamizole is known to induce CYP3A4 and CYP2C19.
Simone D. Baan, Daan J. Touw, Marjolijn N. Lub‐de Hooge, Thijs H. Oude Munnink   +3 more
wiley   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

Ancestral evolution of oxidase activity in a class of (S)-nicotine and (S)-6-hydroxynicotine-degrading flavoenzymes. [PDF]

J Biol Chem
Zhang Z, Bandivadekar PR, Gaunt AJ, Ahn SH, Barkman TJ, Stull F.   +5 more
europepmc   +1 more source

Real‐world population pharmacokinetics of tezacaftor‐ivacaftor in children with cystic fibrosis: The SYM‐CF study

British Journal of Clinical Pharmacology, EarlyView.
Aims The clinical effectiveness of tezacaftor‐ivacaftor in children with cystic fibrosis (cwCF) varies; some patients respond while others do not or have adverse effects. The pharmacokinetics (PK) of tezacaftor‐ivacaftor are inadequately published, especially in children.
Steffie E. M. Vonk, Suzanne W. J. Terheggen‐Lagro, Eric G. Haarman, Hettie M. Janssens, Anke‐Hilse Maitland–van der Zee, E. Marleen Kemper, Ron A. A. Mathôt, on behalf of the Amsterdam Mucociliary Clearance Disease (AMCD) research group   +7 more
wiley   +1 more source

The <i>irpT</i> gene influences the multiple stresses tolerance by affecting cytochrome c in <i>Lactococcus lactis</i> N8. [PDF]

Curr Res Microb Sci
Guo D, Jia C, Xu X, Jiang S, Qiao W, He X, Saris PEJ, Xu H, Qiao M.   +8 more
europepmc   +1 more source