Results 221 to 230 of about 2,499,952 (347)

Synthesis and Application of Bioactive N‐Functionalized Aziridines

open access: yesAngewandte Chemie, EarlyView.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan   +4 more
wiley   +2 more sources

Molecular and Catalytic Properties of the Aldehyde Dehydrogenase of Gluconacetobacter diazotrophicus, a Quinoheme Protein Containing Pyrroloquinoline Quinone, Cytochrome b, and Cytochrome c

open access: yesJournal of Bacteriology, 2010
S. Gómez-Manzo   +7 more
semanticscholar   +1 more source

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

open access: yesAngewandte Chemie, EarlyView.
Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova   +3 more
wiley   +2 more sources

A peroxide bridge between Fe and Cu ions in the O2 reduction site of fully oxidized cytochrome c oxidase could suppress the proton pump

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2009
H. Aoyama   +7 more
semanticscholar   +1 more source

Solvent Channels and Electric Fields Guide Proton Delivery to the Active Site of Heme Peroxidases

open access: yesAngewandte Chemie, EarlyView.
Electrostatic potential surfaces and electric field lines reveal that local fields guide proton delivery through multiple conserved solvent channels in heme peroxidases, enabling efficient access to the active site. Abstract The active sites of heme enzymes have evolved to control the formation of highly reactive intermediates in oxidative catalysis ...
Reynier Suardíaz   +7 more
wiley   +2 more sources

Mitochondrial copper metabolism and delivery to cytochrome c oxidase

open access: yesIUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2008
D. Horn, A. Barrientos
semanticscholar   +1 more source

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