The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
Top-Down Mass Analysis of Protein Tyrosine Nitration: Comparison of Electron Capture Dissociation with “Slow-Heating” Tandem Mass Spectrometry Methods [PDF]
Tyrosine nitration in proteins is an important post-translational modification (PTM) linked to various pathological conditions. When multiple potential sites of nitration exist, tandem mass spectrometry (MS/MS) methods provide unique tools to locate the ...
Cooper, Helen J.+2 more
core +2 more sources
Cellulosic emulsions as multi‐cargo agriculture formulations. Pickering emulsions stabilized by cellulose acetate particles provide an effective platform for delivering a range of agricultural cargoes, including plant growth‐promoting bacteria and agrochemicals.
Mariam Sohail+10 more
wiley +1 more source
The Functional Role of Thiol Groups in Protease-Solubilized NADPH-Cytochrome c Reductase from Pork-Liver Microsomes [PDF]
The total —SH content of protease-solubilized NADPH—cytochrome c reductase (EC 1.6.2.4) from pork liver microsomes was determined to be 5.9 ± 0.3 mol thiol groups per mol of protein. Only three —SH groups of the protease-solubilized NADPH – cytochrome c reductase could be modified by 0.34 or 1.0 mM 5,5′-dithio-bis(2-nitrobenzoate) at pH 7.5 and + 4°C ...
Ludwig Lumper, Helga Ehrig, Tibor Lazar
openaire +3 more sources
Senile Cataract and the Absorption Activity of Cytochrome C Oxidase [PDF]
The aim of the study was to determine the activity of cytochrome c oxidase in mitochondrial fractions of cataractogenic epithelial cells of lenses of 60 patients (34 females and 26 males).
B. Vojniković+3 more
core +1 more source
Crystallization and preliminary structure determination of the membrane-bound complex cytochrome c nitrite reductase from Desulfovibrio vulgaris Hildenborough [PDF]
The cytochrome c nitrite reductase (cNiR) isolated from Desulfovibrio vulgaris Hildenborough is a membrane-bound complex formed of NrfA and NrfH subunits.
Archer, M.+6 more
core +2 more sources
Cell Membrane Vesicle Camouflaged Artificial Cells
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres+11 more
wiley +1 more source
The Effect of Nalidixic Acid Group Compounds on Reduction of Cytochrome c from Horse Heart and Candida krusei [PDF]
Reduction of cytochrome c from both horse heart and Candida krusei by FeSO4 has been demonstrated. This reaction was stimulated by nalidixic acid and structurally related compounds, and the effect was more pronounced for the yeast cytochrome. Divalent metal ions other than Fe2+ lessened or abolished the stimulation by these compounds.
openaire +3 more sources
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan+13 more
wiley +1 more source
Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons [PDF]
Cytochrome c can acquire peroxidase activity when it binds to cardiolipin in mitochondrial membranes. The resulting oxygenation of cardiolipin by cytochrome c provides an early signal for the onset of apoptosis.
Bowler, Bruce E+7 more
core +1 more source