Results 71 to 80 of about 35,768 (229)
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock+7 more
wiley +1 more source
The radical SAM enzyme NirJ is responsible for the removal of two propionate side chains from its substrate didecarboxy‐siroheme during heme d1 biosynthesis. The cleavage products of the NirJ reaction were not known so far. In this study, it is shown that acrylate is formed as the reaction byproduct and that the resulting tetrapyrrole product carries ...
Heike Meyer+5 more
wiley +1 more source
A mass fragmentographic technique for assay of 18-hydroxylation of labeled (exogenous) and unlabeled (endogenous) corticosterone in adrenal mitochondria and in reconstituted cytochrome P-450 systems has been developed.
K E Karlmar
doaj
ABSTRACT Miamiensis avidus (Ciliophora: Scuticociliatida, syn. Philasterides dicentrarchi) is a significant pathogen causing scuticociliatosis in olive flounder (Paralichthys olivaceus) in Korea and Japan. In this study, the BB19 strain, isolated from olive flounder, was identified as M.
Jin‐Young Kim+5 more
wiley +1 more source
Abstract Although outcomes for newly diagnosed acute myeloid leukaemia (AML) have been incrementally improved over the last decades, management of relapsed and refractory (R/R) AML remains a medical challenge. A curative intent for R/R AML usually involves chemotherapy (with or without targeted therapy) with subsequent consolidation, including ...
Martin Jädersten+7 more
wiley +1 more source
Characteristics of the rat liver microsomal enzyme system converting cholecalciferol into 25-hydroxycholecalciferol. Evidence for the participation of cytochrome p-450 [PDF]
Thelma C. Madhok, Hector F. DeLuca
openalex +1 more source
The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen+6 more
wiley +1 more source
Genetic variation among progeny shapes symbiosis in a basidiomycete with poplar
Summary Forest trees rely on ectomycorrhizal (ECM) fungi for acquiring scarce resources such as water and nutrients. However, the molecular mechanisms governing ECM traits remain inadequately understood, particularly the role of intraspecific fungal variation in root‐tip colonisation and trophic interactions.
Benjamin Dauphin+9 more
wiley +1 more source
Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat+6 more
wiley +1 more source
Proposed EU NGT legislation in light of plant genetic variation
Summary The European Commission (EC) proposal for New Genomic Techniques (NGTs) of July 2023 specifies that Category 1 NGT (NGT1) plants, which are considered equivalent to conventional plants, that is those obtainable by conventional plant breeding or mutagenesis, may differ from the recipient or parental plant by no more than 20 insertions, which ...
Alan H. Schulman+6 more
wiley +1 more source