Results 71 to 80 of about 150,542 (166)
, 1993 Characterization of cytochrome P450 1A1 dependent monooxygenases in guinea pig heart revealed low rates of 7-ethoxyresorufin O-deethylation, which are markedly increased (20-fold) by treatment with β-naphthoflavone, a poly cyclic aromatic hydrocarbon ...
Gordon P. McCallum +3 more
core +1 more source
Current Protocols, Volume 6, Issue 5, May 2026.Abstract Alveolar epithelial cell type 1 (AT1) and type 2 (AT2) cells make up the saccular gas exchange units of the lung, called alveoli. Formation of alveoli during lung development accounts for the expansive surface area of the lung, allowing for proper respiration and delivery of oxygen to the body.
Evelyn Tran +11 more
wiley +1 more source
Molecules, 2013 Honokiol is a bioactive component isolated from the medicinal herbs Magnolia officinalis and Magnolia grandiflora that has antioxidative, anti-inflammatory, antithrombotic, and antitumor activities.
Yong Yeon Cho +8 more
doaj +1 more source
Resveratrol for Cancer Radio‐Sensitization: Ready for Prime Time or Future Perspective
Food Science &Nutrition, Volume 14, Issue 5, May 2026.Resveratrol exerts antioxidant and anti‐inflammatory effects by reducing reactive oxygen species and suppressing NF‐κB and JAK/STAT signaling pathways. It modulates metabolic signaling through AMPK‐dependent inhibition of mTOR, influencing cell survival and inflammatory responses.
Maryam Fallah +7 more
wiley +1 more source
Heterologous expression and purification of rat cytochrome P450 1A1 [PDF]
, 2013 Cytochrome P450 1A1 belongs to "superfamily" of cytochromes P450 (CYPs). It is an extrahepatic enzyme that takes a part in detoxification metabolism of many xenobiotics but unfortunately also it is one of the most important representatives of CYPs ...
Vlková, Michaela
core
Polymorphism of the cytochrome P-450 1A1 (A2455G) in women with breast cancer in Eastern Azerbaijan, Iran [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s):Cytochrome P-450 1A1 is an important enzyme in the first phase of the metabolism of some carcinogens such as polycyclic aromatic hydrocarbons (PAHs), as well as estrogen.
Hakimeh Saadatian +4 more
doaj
Notulae Scientia Biologicae, 2019 The CYP family enzymes are broadly used as biomarkers because of their pattern of expression. This study describes the application of in silico tools to predict the physico-chemical characters of CYP1A protein from the catfish, Clarias gariepinus.
Muthuramalingam KARPAGAVALLI +5 more
doaj +1 more source
Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension
British Journal of Pharmacology, Volume 183, Issue 9, Page 1824-1844, May 2026.Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam +12 more
wiley +1 more source
Cytochromes P450 : from model compounds towards artificial hemoproteins [PDF]
, 2007 Cytochromes P450 are heme-thiolate proteins abundant in nature. These monooxygenases catalyse a variety of reactions including alkene epoxixation, N-, O-, and S-dealkylation, C-C bond cleavage and hydrocarbon hydroxylation.
Büttiker, Dominik
core +1 more source
International Journal of Electrochemical Science, 2013 The antineoplastic alkaloid ellipticine is a prodrug, the pharmacological efficiency of which is dependent on its cytochrome P450 (CYP)- and/or peroxidase-mediated activation in target tissues.
Iveta Vranová +5 more
doaj +1 more source