Results 81 to 90 of about 150,542 (166)

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer [PDF]

, 2014
Peer ...
Petronella Johansson, Johansson, Petronella, Gordon T Brown, Gordon T. Brown (532127), Beatriz Gimenez Cash, Beatriz Gimenez Cash (532128), Ayham Alnabulsi (532130), Graeme I. Murray (195455), Daniela Blihoghe, Cash, Beatriz Giminez, Alnabulsi, Ayham, Daniela Blihoghe (472704), Brown, Gordon T, Graeme I Murray, Ayham Alnabulsi, Petronella Johansson (532129), Blihoghe, Daniela, Murray, Graeme I   +17 more
core   +2 more sources

Indole compounds from fermented soybean products activate the aryl hydrocarbon receptor to reduce liver injury

npj Science of Food
The consumption of stinky tofu, a traditional fermented soybean product from China, elevates the concentrations of indole and trimethylindole in murine feces and increases the levels of indole in serum, as well as indole in the liver.
Yanyun Wang, Leping Quan, Xiaomin Zheng, Qiang Hu, Xiaoli Huang, Yang Pu, Guangfa Xie, Qi Peng   +7 more
doaj   +1 more source

Molecular simulations on proteins of biomedical interest : A. Ligand-protein hydration B. Cytochrome P450 2D6 and 2C9 C. Myelin associated glycoprotein (MAG) [PDF]

, 2011
TOPIC 1: Water molecules mediating polar interactions in ligand–protein complexes contribute to both binding affinity and specificity. To account for such water molecules in computer-aided drug discovery, we performed an extensive search in the Cambridge
Rossato, Gianluca
core   +1 more source

Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date

Molecules, 2017
The cytochrome P450 (CYP) family 1A enzymes, CYP1A1 and CYP1A2, are two of the most important enzymes implicated in the metabolism of endogenous and exogenous compounds through oxidation.
Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu, Maryam Foroozesh   +3 more
doaj   +1 more source

OSSERVAZIONI SULL’ATTIVAZIONE DEL RECETTORE ARILICO (AHR) IN CORRELAZIONE ALLA CONTAMINAZIONE AMBIENTALE DA METALLI PESANTI IN TUMORI SPONTANEI DI CANI DELLA REGIONE CAMPANIA. Correlation between Aryl hydrocarbon Receptor (AhR ) expression and environmental heavy metals contamination in canine tumors. [PDF]

, 2010
Osservazioni sull’attivazione del recettore arilico (Ahr) in correlazione alla contaminazione ambientale da metalli pesanti in tumori spontanei di cani della regione Campania.
Trapani, Francesca
core   +1 more source

Inhibition of Cytochrome P450 Activities by Extracts of Hyptis verticillata Jacq.: Assessment for Potential HERB-Drug Interactions

Molecules, 2018
Understanding the potential for adverse drug reactions (ADRs), from herb-drug interactions, is a key aspect of medicinal plant safety, with particular relevance for public health in countries where medicinal plant use is highly prevalent. We undertook an
David Picking, Bentley Chambers, James Barker, Iltaf Shah, Roy Porter, Declan P Naughton, Rupika Delgoda   +6 more
doaj   +1 more source

Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1A1: a CO flash photolysis study.

, 1996
The kinetics of CO binding to human cytochrome P450 1A1 was used to probe the interaction of polycyclic aromatic hydrocarbons (PAHs) with the membrane-bound P450 expressed in baculovirus-infected SF9 insect cells.
Koley, AP;Buters, JT;Robinson, RC;Markowitz, A;Friedman, FK
core   +1 more source

A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response [PDF]

, 2008
The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are closely related orphan nuclear hormone receptors that play a critical role as xenobiotic sensors in mammals.
Zevnik, Branko, Rode, Anja, Nicole Faust, Ross, Jillian, C. Roland Wolf, Nico Scheer, Scheer, Nico, Niehaves, Sandra, Sandra Niehaves, Faust, Nicole, Branko Zevnik, Wolf, C. Roland, Jillian Ross, Anja Rode   +13 more
core   +1 more source

Transcrição de genes citocromo P450 em ostra Crassostrea gigas [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2013Diversas áreas costeiras no Estado de Santa Catarina estão associadas a zonas de ...
Gomes, Rafaela Pino
core  

Identification and Analysis of Hub Genes in Diabetic Cardiomyopathy: Potential Role of Cytochrome P450 1A1 in Mitochondrial Metabolism and STZ-Induced Myocardial Dysfunction. [PDF]

Front Cardiovasc Med, 2022
Chen Y, Chen Y, Yang J, Wang Y, Shen W, Liu J, Yuan M, Hao X, Zhong L, Guo R.   +9 more
europepmc   +1 more source