Results 151 to 160 of about 25,921 (203)

Translational Medicine in Alzheimer's Disease: The Journey of Donanemab From Discovery to Clinical Application

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Donanemab, approved by the U.S. FDA in July 2024, targets amyloid plaques in the brain to treat Alzheimer's disease in patients with mild cognitive impairment or mild dementia. ABSTRACT Substantial research has been conducted to identify an efficient treatment for Alzheimer's disease (AD).
Nandhini Jayaprakash   +1 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

b-Type Cytochromes

Annual Review of Biochemistry, 1980
No abstract ...
von Jagow, Gerhard, Sebald, Walter
openaire   +4 more sources

Mammalian Cytochrome b

Science, 1959
Digestion of a preparation of cytochromes b and c 1 with pancreatic protease followed by ammonium sulfate precipitation resulted in a soluble cytochrome b uncontaminated by cytochrome c 1 .
W.W. Wainio, Donald Feldman
openaire   +2 more sources

Assembly of chloroplast cytochromes b and c [PDF]

open access: possibleBiochimie, 2000
The synthesis of holocytochromes in plastids is a catalyzed process. Several proteins, including plastid CcsA, Ccs1, possibly CcdA and a thioredoxin, plus at least two additional Ccs factors, are required in sub-stoichiometric amounts for the conversion of apocytochromes f and c(6) to their respective holoforms.
Sabeeha S. Merchant   +2 more
openaire   +2 more sources

Reduction kinetics of cytochromes b

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1972
Abstract 1. 1. Durohydroquinone (H2DQ), a specific reductant for the second phosphorylation site, has been used in the study of the fast reduction kinetics of cytochromes b. 2. 2. In ubiquinone-extracted mitochondria, H2DQ reduces cytochrome(s) b in a fast reaction, the rate and extent of which decreases upon reincorporation of ubiquinone ...
Alberto Boveris   +2 more
openaire   +3 more sources

Evaluation of the Cytochrome b5/Cytochrome b5 Reductase Pathway

Current Protocols in Toxicology, 2005
AbstractNADH cytochrome b5 reductase (b5R; EC 1.6.2.2; Diaphorase I; NADH: ferricytochrome b5 oxidoreductase) is an FAD‐containing protein, which, along with the hemoprotein cytochrome b5 (cyt b5), mediates electron transfer from NADH to fatty acid desaturases, P450 oxidases, methemoglobin, and ascorbyl free radical.
Joseph R. Kurian   +2 more
openaire   +3 more sources

On the Structure and Function of Cytochrome b-559

Photosynthesis Research, 1986
A sumary of biochemical, biophysical, and molecular biological data is presented which led to the identification of two different polypeptides (α and β, MW=9.16 and 4.27 kDa) in the cytochrome b-559 protein. The presence of a single His residue on each polypeptide, and the conclusion from spectroscopy that the heme coordination must be bis-histidine ...
William A. Cramer   +2 more
openaire   +3 more sources

Halobacterium halobium Cytochrome b-558 and Cytochrome b-562: Purification and Some Properties

The Journal of Biochemistry, 1993
Four different membrane-bound b-type cytochromes were found to occur in Halobacterium halobium strain L-33, and two of them, b-558 and b-562, were purified to homogeneity. Cytochrome b-558 showed absorption peaks at 414 and 526 nm in the oxidized form, and peaks at 425, 528, and 558 nm in the reduced form.
Tateo Yamanaka   +2 more
openaire   +3 more sources

Cytochrome b and photosynthetic sulfur bacteria

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1975
Chromatophores isolated from the purple sulfur bacterium Chromatium and the green sulfur bacterium Chlorobium exhibit absorbance changes in the cytochrome alpha-band region consistent with the presence of a b-type cytochrome. Cytochrome content determined by reduced minus oxidized difference spectra and by heme photochemically active ...
David B. Knaff, Bob B. Buchanan
openaire   +3 more sources

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