Results 11 to 20 of about 56,650 (349)

Novel Essential Role of Ethanol Oxidation Genes at Low Temperature Revealed by Transcriptome Analysis in the Antarctic Bacterium Pseudomonas extremaustralis. [PDF]

open access: yesPLoS ONE, 2015
Temperature is one of the most important factors for bacterial growth and development. Cold environments are widely distributed on earth, and psychrotolerant and psychrophilic microorganisms have developed different adaptation strategies to cope with the
Paula M Tribelli   +6 more
doaj   +6 more sources

The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]

open access: yes, 2020
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae   +6 more
core   +2 more sources

Multi-heme Cytochromes in Shewanella oneidensis MR-1:Structures, functions and opportunities [PDF]

open access: yes, 2015
Multi-heme cytochromes are employed by a range of microorganisms to transport electrons over distances of up to tens of nanometers. Perhaps the most spectacular utilization of these proteins is in the reduction of extracellular solid substrates ...
Brown JP   +9 more
core   +1 more source

Metabolome and Transcriptome Analyses of Cucurbitacin Biosynthesis in Luffa (Luffa acutangula)

open access: yesFrontiers in Plant Science, 2022
Cucurbitacins are extremely bitter compounds mainly present in Cucurbitaceae, where Luffa belongs. However, there is no comprehensive analysis of cucurbitacin biosynthesis in Luffa fruit.
Gangjun Zhao   +9 more
doaj   +1 more source

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

open access: yes, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W.   +50 more
core   +1 more source

Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity

open access: yesBiomedicines, 2020
Herein, the in vitro metabolism of tyrosine kinase inhibitor cabozantinib, the drug used for the treatment of metastatic medullary thyroid cancer and advanced renal cell carcinoma, was studied using hepatic microsomal samples of different human donors ...
Radek Indra   +4 more
doaj   +1 more source

Genome-enabled studies of anaerobic, nitrate-dependent iron oxidation in the chemolithoautotrophic bacterium Thiobacillus denitrificans

open access: yesFrontiers in Microbiology, 2013
Thiobacillus denitrificans is a chemolithoautotrophic bacterium capable of anaerobic, nitrate-dependent U(IV) and Fe(II) oxidation, both of which can strongly influence the long-term efficacy of in situ reductive immobilization of uranium in contaminated
Harry R Beller   +7 more
doaj   +1 more source

Biogenesis of mitochondrial c-type cytochromes [PDF]

open access: yes, 1990
Cytochromesc andc 1 are essential components of the mitochondrial respiratory chain. In both cytochromes the heme group is covalently linked to the polypeptide chain via thioether bridges. The location of the two cytochromes is in the intermembrane space;
Gonzales, Daniel H., Neupert, Walter
core   +2 more sources

Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:Benzo(a)pyrene (BaP), naphthalene (NPh), phenanthrene (Phe), benzo(a)antharacene (BeA), and benzo(b)fluoranthene (BeF) are known carcinogenic polyaryl hydrocarbons (PAHs) present in cigarette smoke.
Sabina Ranjit   +7 more
doaj   +1 more source

The relay network of Geobacter biofilms [PDF]

open access: yes, 2018
While actual models explaining electron conduction in electricity producing biofilms have evolved separately to apparent irreconcilable conceptual positions, finding cytochrome complexes in the external matrix of Geobacter biofilms supports the proposal ...
Busalmen, Juan Pablo   +3 more
core   +1 more source

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