Results 31 to 40 of about 115,090 (246)

Cell-based Immunotherapy for Colorectal Cancer with Cytokine-induced Killer Cells [PDF]

open access: yesImmune Network, 2016
Colorectal cancer is the third leading cancer worldwide. Although incidence and mortality of colorectal cancer are gradually decreasing in the US, patients with metastatic colorectal cancer have poor prognosis with an estimated 5-year survival rate of less than 10%.
Kim, Ji Sung   +7 more
openaire   +2 more sources

Enhancing cytokine-induced killer cell therapy of multiple myeloma [PDF]

open access: yesExperimental Hematology, 2013
Cytokine-induced killer (CIK) cells are in clinical testing against various tumor types, including multiple myeloma. In this study, we show that CIK cells have activity against subcutaneous and disseminated models of human myeloma (KAS-6/1), which can be enhanced by infecting the CIK cells with an oncolytic measles virus (MV) or by pretreating the ...
Chunsheng, Liu   +4 more
openaire   +2 more sources

Functional invariant natural killer T-cell and CD1d axis in chronic lymphocytic leukemia: implications for immunotherapy

open access: yesHaematologica, 2013
Invariant natural killer T cells recognize glycolipid antigens such as α-galactosylceramide presented by CD1d. In preclinical models of B-cell malignancies, α-galactosylceramide is an adjuvant to tumor vaccination, enhancing tumor-specific T-cell ...
Robert Weinkove   +4 more
doaj   +1 more source

Rapid response of advanced squamous non-small cell lung cancer with thrombocytopenia after first-line treatment with pembrolizumab plus autologous cytokine-induced killer cells

open access: yesFrontiers in Immunology, 2015
We present the first clinical evidence of advanced squamous non-small cell lung cancer with severe thrombocytopenia showing dramatic improvement after first-line treatment with pembrolizumab plus cytokine-induced killer cells.
Zhenzhen eHui   +4 more
doaj   +1 more source

Cytokine-induced killer cell/dendritic cell–cytokine-induced killer cell immunotherapy for the postoperative treatment of gastric cancer

open access: yesMedicine, 2018
Immunotherapy is emerging as a new treatment strategy for gastric cancer(GC). However, the efficacy and safety of this technique remain unclear. This meta-analysis aimed to assess the effect of cytokine-induced killer cell (CIK)/dendritic cell-cytokine-induced killer cell (DC-CIK) treatment for GC after surgery.Hazard ratio (HR), overall survival (OS ...
Wang, Xiang   +7 more
openaire   +2 more sources

Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer in China: a meta-analysis

open access: yesOncoTargets and Therapy, 2017
Immunotherapy based on cytokine-induced killer cells or combination of dendritic cells and cytokine-induced killer cells (CIK/DC-CIK) showed promising clinical outcomes for treating esophageal cancer (EC). However, the clinical benefit varies among previous studies.
Yan Liu   +7 more
openaire   +4 more sources

Treatment of multiple solitary plasmacytomas with cytokine-induced killer cells [PDF]

open access: yesCytotherapy, 2014
Currently available treatment methods for advanced plasmacytoma include surgery, chemotherapy, radiotherapy, immunomodulatory agents, hematopoietic stem cell transplantation and donor lymphocyte infusion. We report a case of advanced refractory multiple solitary plasmacytomas in a 68-year-old Asian man with multiple bone lesions, in whom autologous ...
Bo, Yang   +6 more
openaire   +2 more sources

Adjuvant alternative cytokine-induced killer cell combined with natural killer cell immunotherapy improves the prognosis of post-mastectomy breast cancer

open access: yesFrontiers in Immunology, 2022
Breast cancer is one of the most common cancers in women. Triple-negative breast cancer (TNBC) has a significantly worse prognosis due to the lack of endocrine receptors including estrogen receptor (ER), progesterone receptor (PR) and human epidermal ...
Xinyi Yang   +20 more
doaj   +1 more source

The efficacy and safety of the combination of axitinib and pembrolizumab‐activated autologous DC‐CIK cell immunotherapy for patients with advanced renal cell carcinoma: a phase 2 study

open access: yesClinical & Translational Immunology, 2021
Objectives Although axitinib has achieved a preferable response rate for advanced renal cell carcinoma (RCC), patient survival remains unsatisfactory. In this study, we evaluated the efficacy and safety of a combination treatment of axitinib and a low ...
Meng‐Jia Song   +29 more
doaj   +1 more source

Advances in research based on antibody-cell conjugation

open access: yesFrontiers in Immunology, 2023
Antibody-cell conjugation (ACC) technology is a new research direction in medicine and biotechnology in recent years. The concept of ACC was proposed by Hsiao et al.
Xiaoxuan Ma   +8 more
doaj   +1 more source

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