Results 21 to 30 of about 1,542,731 (346)
Engineering cytokines and cytokine circuits
Learning to speak the secret language of immune cells could improve ...
Wendell A. Lim, Aileen W. Li
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The transcriptional activity of the glucocorticoid receptor (GR) is co-determined by its ability to recruit a vast and varying number of cofactors. We here identify Striatin-3 (STRN3) as a novel interaction partner of GR that interferes with GR’s ligand ...
Ioanna Petta+12 more
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The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease
Castleman disease is a polyclonal lymphoproliferative disorder characterized by unicentric or multicentric lymphadenopathy with characteristic histomorphological features, in addition to variable inflammatory symptomatology. The molecular mechanisms and
Pedro Horna+4 more
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Principles of interleukin (IL)-6-type cytokine signalling and its regulation.
The IL (interleukin)-6-type cytokines IL-6, IL-11, LIF (leukaemia inhibitory factor), OSM (oncostatin M), ciliary neurotrophic factor, cardiotrophin-1 and cardiotrophin-like cytokine are an important family of mediators involved in the regulation of the ...
P. Heinrich+5 more
semanticscholar +1 more source
Natural products and traditional herbal medicine are an important source of alternative bioactive compounds but very few plant-based preparations have been scientifically evaluated and validated for their potential as medical treatments.
Alejandra Gomez-Cadena+3 more
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α1-Antitrypsin (AAT) is a member of the serine proteinase inhibitor family that impedes the enzymatic activity of serine proteinases, including human neutrophil elastase, cathepsin G and neutrophil proteinase 3.
Siyoung Lee+11 more
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Curcumin (diferuloylmethane), a golden pigment from turmeric, has been linked with antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, and antidiabetic properties. Most of the these activities have been assigned to methoxy, hydroxyl, α,
Bharat B. Aggarwal+2 more
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C57BL/6 mice are one of the most widely used inbred strains in biomedical research. Early separation of the breeding colony has led to the development of several sub-strains.
Nada Abdel Aziz+10 more
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Cytokine Modulation of Keratinocyte Cytokines
There is increasing evidence that epidermal cytokines may have an important role in mediating inflammatory and immune responses in the skin. A number of cell types in the epidermis are capable of secreting cytokines including keratinocytes, Langerhans cells, melanocytic cells, and even Merkle cells.
Stephen H. Hefeneider+7 more
openaire +3 more sources
Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has caused 347,192 deaths around the world.
Yujun Tang+5 more
semanticscholar +1 more source