Results 21 to 30 of about 2,162,469 (384)

Cytokine gene polymorphisms in preterm infants with necrotising enterocolitis: genetic association study [PDF]

, 2016
BACKGROUND The inflammatory cytokine cascade is implicated in the pathogenesis of necrotising enterocolitis (NEC). Genetic association studies of cytokine polymorphisms may help to detect molecular mechanisms that are causally related to the disease ...
Baier, R. J., Brocklehurst, P., Craig, S., Helps, N., Henderson, G., McGuire, W.   +5 more
core   +1 more source

Cytokines and Disease [PDF]

Mediators of Inflammation, 2014
Recent evidence in biology and medicine has expanded the knowledge of cytokines function in many disease states and conditions as well as the severe adverse effects implicated in the escalated production associated with specific disease conditions.
Arkadiusz Orzechowski, Agueda A. Rostagno, Sabina Pucci, Gilles Chiocchia   +3 more
openaire   +5 more sources

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

Seminars in Immunopathology, 2017
Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild, cold-like respiratory illness.
Rudragouda Channappanavar, S. Perlman
semanticscholar   +1 more source

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Scientific Reports, 2017
The transcriptional activity of the glucocorticoid receptor (GR) is co-determined by its ability to recruit a vast and varying number of cofactors. We here identify Striatin-3 (STRN3) as a novel interaction partner of GR that interferes with GR’s ligand ...
Ioanna Petta, Nadia Bougarne, Jolien Vandewalle, Lien Dejager, Sofie Vandevyver, Marlies Ballegeer, Sofie Desmet, Jonathan Thommis, Lode De Cauwer, Sam Lievens, Claude Libert, Jan Tavernier, Karolien De Bosscher   +12 more
doaj   +1 more source

Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: A multicenter study [PDF]

, 2008
The increase of proinflammatory cytokines in vaginal secretions may serve as a surrogate marker of unwanted inflammatory reaction to microbicide products topically applied for the prevention of sexually transmitted diseases, including HIV-1. Interleukin (
Alfano, M, Belec, L, Carbonneil, C, Chen, S, Cosentino, L, Cummins, JE, Curtis, K, Dezzutti, CS, Donaghay, M, Doncel, GF, Donoval, B, Fichorova, RN, Grivel, JC, Guzman, E, Hayes, M, Herold, B, Hillier, S, Lackman-Smith, C, Landay, A, Margolis, L, Mayer, KH, Pallansch-Cokonis, M, Pasicznyk, JM, Poli, G, Reichelderfer, P, Richardson-Harman, N, Roberts, P, Rodriguez, I, Saidi, H, Sassi, RR, Shattock, R   +30 more
core   +2 more sources

Engineering cytokines and cytokine circuits

Science, 2020
Learning to speak the secret language of immune cells could improve ...
Wendell A. Lim, Aileen W. Li
openaire   +4 more sources

COVID-19 spike polypeptide vaccine reduces the pathogenesis and viral infection in a mouse model of SARS-CoV-2

Frontiers in Immunology, 2023
The SARS-CoV-2 coronavirus, which causes a respiratory disease called COVID-19, has been declared a pandemic by the World Health Organization (WHO) and is still ongoing. Vaccination is the most important strategy to end the pandemic.
Yasmin Hisham, Sun-Min Seo, Sinae Kim, Sinae Kim, Saerok Shim, Jihyeong Hwang, Eun-Seon Yoo, Na-Won Kim, Chang-Seon Song, Hyunjhung Jhun, Ho-Young Park, Youngmin Lee, Kyeong-Cheol Shin, Sun-Young Han, Je Kyung Seong, Je Kyung Seong, Yang-Kyu Choi, Soohyun Kim, Soohyun Kim   +18 more
doaj   +1 more source

Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. [PDF]

, 2013
BackgroundBrucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú.
Feldman, Kristyn E, Gilman, Robert H, Gotuzzo, Eduardo, Hoffmann, Alexander, Loriaux, Paul M, Saito, Mayuko, Siva, Tenaya, Tuero, Iskra, Villaverde, Homarh, Vinetz, Joseph M   +9 more
core   +3 more sources

Effect of Recombinant α1-Antitrypsin Fc-Fused (AAT-Fc) Protein on the Inhibition of Inflammatory Cytokine Production and Streptozotocin-Induced Diabetes

Molecular Medicine, 2013
α1-Antitrypsin (AAT) is a member of the serine proteinase inhibitor family that impedes the enzymatic activity of serine proteinases, including human neutrophil elastase, cathepsin G and neutrophil proteinase 3.
Siyoung Lee, Youngmin Lee, Kwangwon Hong, Jaewoo Hong, Suyoung Bae, Jida Choi, Hyunjhung Jhun, Areum Kwak, Eunsom Kim, Seunghyun Jo, Charles A. Dinarello, Soohyun Kim   +11 more
doaj   +1 more source

The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease

Haematologica, 2022
Castleman disease is a polyclonal lymphoproliferative disorder characterized by unicentric or multicentric lymphadenopathy with characteristic histomorphological features, in addition to variable inflammatory symptomatology. The molecular mechanisms and
Pedro Horna, Rebecca L. King, Dragan Jevremovic, David C. Fajgenbaum, Angela Dispenzieri   +4 more
doaj   +1 more source