Results 11 to 20 of about 2,857,482 (280)

Cytokine Release Syndrome: An Overview on its Features and Management

Journal of Pure and Applied Microbiology, 2019
Cytokine release syndrome (CRS) is a life threatening toxicity associated numerous immunotherapeutic techniques involving monoclonal antibodies, bispecific antibodies and adoptive T cell therapies. It is also referred as infusion reaction that results in
Shailza Shreshtha, Pradeep Kumar, Preeti Sharma, Rachna Sharma   +3 more
doaj   +2 more sources

Cytokine release syndrome treated with tocilizumab following ipilimumab–nivolumab combination therapy in advanced renal cell carcinoma

IJU Case Reports
Introduction Cytokine release syndrome is a rare but potentially life‐threatening complication of immune checkpoint inhibitor therapy. Its occurrence in renal cell carcinoma treated with combination therapy is less recognized and poses significant ...
Toru Inoue, Akiko Todaka, Masahiro Fuse, Shuntaro Suzuki, Shinya Sejiyama, Tadasuke Ando, Toshitaka Shin   +6 more
doaj   +2 more sources

DeltaRex-G, tumor targeted retrovector encoding a CCNG1 inhibitor, for CAR-T cell therapy induced cytokine release syndrome [PDF]

Frontiers in Molecular Medicine
Cytokine release syndrome is a serious complication of chimeric antigen receptor-T cell therapy and is triggered by excessive secretion of inflammatory cytokines by chimeric T cells which could be fatal. Following an inquiry into the molecular mechanisms
Grace Haroun, Erlinda M. Gordon
doaj   +2 more sources

Cytokine Release Syndrome (CRS) and Nicotine in COVID-19 Patients: Trying to Calm the Storm

Frontiers in Immunology, 2020
SARS-CoV-2 is a new coronavirus that has caused a worldwide pandemic. It causes severe acute respiratory syndrome (COVID-19), which is fatal in many cases, and is characterized by a cytokine release syndrome (CRS).
Jesus Gonzalez-Rubio, Carmen Navarro-Lopez, Elena Lopez-Najera, Ana Lopez-Najera, Lydia Jimenez-Diaz, Juan D. Navarro-Lopez, Alberto Najera   +6 more
doaj   +2 more sources

Severe Cytokine Release Syndrome and Hemophagocytic Lymphohistiocytosis (HLH)-Like Syndrome Following Administration of Combined Brentuximab Vedotin and Nivolumab for Recurrent Classical Hodgkin Lymphoma: A Case Report

Journal of Blood Medicine
Osama Mosalem,1 Tanmayi Pai,1 Mohammed Alqawasma,2 Marwan Shaikh,1 K David Li,3 Muhamad Alhaj Moustafa1 1Department of Hematology/Oncology, Mayo Clinic, Jacksonville, FL, USA; 2Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville ...
Mosalem O, Pai T, Alqawasma M, Shaikh M, Li KD, Alhaj Moustafa M   +5 more
doaj   +1 more source

Successful immunomodulation in kidney transplant recipients with cytokine release syndrome after coronavirus disease

IJU Case Reports, 2022
Introduction Patients with coronavirus disease, especially solid organ transplant recipients, are more susceptible to developing cytokine release syndrome than those with other viral infections.
Daiji Takamoto, Hajime Sasaki, Hiroshi Kataoka, Fumihiro Kodama, Haruka Higuchi, Tetsuo Hirano, Yusuke Takada, Shigeru Harada, Hiroshi Harada, Hiroshi Tanaka   +9 more
doaj   +1 more source

Cytokine Release Syndrome Following Blinatumomab Therapy [PDF]

Cureus, 2022
New therapeutic solutions have emerged in the last few decades with the growth and expansion of the field of cancer research. Amongst these new agents, immunotherapy has been prominent, particularly regarding the treatment of hematologic malignancies.
Ojemolon, Pius E, Kalidindi, Sunaina, Ahlborn, Taylor A, Aihie, Osaigbokan P, Awoyomi, Moyosoluwa I   +4 more
openaire   +2 more sources

Collapsing Focal Segmental Glomerulosclerosis and Acute Kidney Injury Associated With Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: A Case Report

Kidney Medicine, 2021
Chimeric antigen receptor T (CAR-T) cell treatment is a rapidly emerging therapy for relapsed/refractory hematologic malignancies. Although cytokine release syndrome is a common complication, a concomitant development of biopsy-proven collapsing ...
Ratna Acharya, Biljana Horn, Xu Zeng, Kiran Upadhyay   +3 more
doaj   +1 more source

Description and Analysis of Cytokine Storm in Registered COVID-19 Clinical Trials: A Systematic Review

Pathogens, 2021
The purpose of this systematic review was to describe the characteristics of clinical trials that focused on COVID-19 patients with cytokine release syndrome (CRS) and the variability in CRS definitions.
Khalid Eljaaly, Husam Malibary, Shaimaa Alsulami, Muradi Albanji, Mazen Badawi, Jaffar A. Al-Tawfiq   +5 more
doaj   +1 more source

Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report

Терапевтический архив, 2021
Сytokine release syndrome is the common complication of CAR-T therapy. We report a case of patient with B-cell acute lymphoblastic leukemia developing сytokine release syndrome with shock and multiple organ failure and requiring cytokine removal and ...
Antonina E. Shchekina, Gennadii M. Galstyan, Olga A. Gavrilina, Natalia M. Arapova, Svetlana Iu. Bronyakina, Ekaterina S. Kotova, Vera V. Troitskaya, Elena N. Parovichnikova, Mikhail A. Maschan, Valerii G. Savchenko   +9 more
doaj   +1 more source