Results 21 to 30 of about 318,819 (293)

Cytokine release syndrome in severe COVID-19 [PDF]

open access: yesScience, 2020
Lessons from arthritis and cell therapy in cancer patients point to therapy for severe ...
Moore, John B., June, Carl H.
openaire   +2 more sources

Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report

open access: yesТерапевтический архив, 2021
Сytokine release syndrome is the common complication of CAR-T therapy. We report a case of patient with B-cell acute lymphoblastic leukemia developing сytokine release syndrome with shock and multiple organ failure and requiring cytokine removal and ...
Antonina E. Shchekina   +9 more
doaj   +1 more source

Description and Analysis of Cytokine Storm in Registered COVID-19 Clinical Trials: A Systematic Review

open access: yesPathogens, 2021
The purpose of this systematic review was to describe the characteristics of clinical trials that focused on COVID-19 patients with cytokine release syndrome (CRS) and the variability in CRS definitions.
Khalid Eljaaly   +5 more
doaj   +1 more source

Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy [PDF]

open access: yesNature Reviews Immunology, 2021
A paradigm shift has recently occurred in the field of cancer therapeutics. Traditional anticancer agents, such as chemotherapy, radiotherapy and small-molecule drugs targeting specific signalling pathways, have been joined by cellular immunotherapies based on T cell engineering.
Emma C. Morris   +3 more
openaire   +3 more sources

The Many Faces of JAKs and STATs Within the COVID-19 Storm

open access: yesFrontiers in Immunology, 2021
The positive-sense single stranded RNA virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), resulted in a global pandemic with horrendous health and economic consequences not seen in a century.
Alice H. Grant   +8 more
doaj   +1 more source

Efficacy of Single Tocilizumab Administration in an 88-Year-Old Patient with Severe COVID-19 and a Mini Literature Review

open access: yesGeriatrics, 2022
The new coronavirus disease 2019 (COVID-19) could be associated with elevated inflammatory cytokine levels, suggesting the involvement of cytokine release syndrome.
Cid Ould Ouali   +10 more
doaj   +1 more source

Enhanced release of elastase is not concomitant with increased secretion of granulocyte-activating cytokines in whole blood from patients with sepsis [PDF]

open access: yes, 1994
Die Diskussion am Ende des Artikels wurde gelöscht (§137l UrhG).Background The proteolytic enzyme elastase released by granulocytes (polymorphonuclear leukocytes [PMN]) in high concentrations during sepsis causes degradation of essential plasma proteins,
Ertel, Wolfgang   +6 more
core   +1 more source

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

open access: yesEmerging Microbes and Infections, 2021
SARS-CoV-2 has claimed 2,137,908 lives in more than a year. Some COVID-19 patients experience sudden and rapid deterioration with the onset of fatal cytokine storm syndrome (CSS), which have increased interest in CSS’s mechanisms, diagnosis and therapy ...
Xi Yongzhi
doaj   +1 more source

Rituximab induced pulmonary edema managed with extracorporeal life support [PDF]

open access: yes, 2018
Though rare, rituximab has been reported to induce severe pulmonary edema. We describe the first report of ECLS utilization for this indication. A 31-year-old female with severe thrombotic thrombocytopenic purpura developed florid pulmonary edema after ...
Aguilar, Patrick   +6 more
core   +3 more sources

Highly sensitive in vitro cytokine release assay incorporating high-density preculture

open access: yesJournal of Immunotoxicology, 2021
Immunostimulatory effects of monoclonal antibodies (mAb) through binding to Fcγ receptors (FcγR) on immune cells are a likely cause of cytokine release syndrome.
Shiho Ito   +5 more
doaj   +1 more source

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