Results 21 to 30 of about 193,929 (276)

Cytokine release syndrome in severe COVID-19 [PDF]

open access: yesScience, 2020
Lessons from arthritis and cell therapy in cancer patients point to therapy for severe ...
Moore, John B., June, Carl H.
openaire   +2 more sources

Description and Analysis of Cytokine Storm in Registered COVID-19 Clinical Trials: A Systematic Review

open access: yesPathogens, 2021
The purpose of this systematic review was to describe the characteristics of clinical trials that focused on COVID-19 patients with cytokine release syndrome (CRS) and the variability in CRS definitions.
Khalid Eljaaly   +5 more
doaj   +1 more source

The Many Faces of JAKs and STATs Within the COVID-19 Storm

open access: yesFrontiers in Immunology, 2021
The positive-sense single stranded RNA virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), resulted in a global pandemic with horrendous health and economic consequences not seen in a century.
Alice H. Grant   +8 more
doaj   +1 more source

Efficacy of Single Tocilizumab Administration in an 88-Year-Old Patient with Severe COVID-19 and a Mini Literature Review

open access: yesGeriatrics, 2022
The new coronavirus disease 2019 (COVID-19) could be associated with elevated inflammatory cytokine levels, suggesting the involvement of cytokine release syndrome.
Cid Ould Ouali   +10 more
doaj   +1 more source

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

open access: yesEmerging Microbes and Infections, 2021
SARS-CoV-2 has claimed 2,137,908 lives in more than a year. Some COVID-19 patients experience sudden and rapid deterioration with the onset of fatal cytokine storm syndrome (CSS), which have increased interest in CSS’s mechanisms, diagnosis and therapy ...
Xi Yongzhi
doaj   +1 more source

Cardiovascular Complications of Chimeric Antigen Receptor T-Cell Therapy: The Cytokine Release Syndrome and Associated Arrhythmias [PDF]

open access: yesJournal of Immunotherapy and Precision Oncology, 2020
In recent years, cancer treatment has evolved, and new therapies have been introduced with significant improvement in prognosis. The immunotherapies stand out owing to their efficacy and remission rate. Chimeric antigen receptor (CAR) T-cell therapy is a
Cesar Clavijo Simbaqueba   +9 more
doaj   +1 more source

Highly sensitive in vitro cytokine release assay incorporating high-density preculture

open access: yesJournal of Immunotoxicology, 2021
Immunostimulatory effects of monoclonal antibodies (mAb) through binding to Fcγ receptors (FcγR) on immune cells are a likely cause of cytokine release syndrome.
Shiho Ito   +5 more
doaj   +1 more source

STAT: Cytokine Release Syndrome

open access: yesClinical Journal of Oncology Nursing, 2020
Cytokine release syndrome is a systemic inflammatory condition that may occur after treatment with some types of immunotherapy.
openaire   +3 more sources

Interleukin Inhibitors in Cytokine Release Syndrome and Neurotoxicity Secondary to CAR-T Therapy

open access: yesDiseases, 2022
Introduction: Chimeric antigen receptor T-cell (CAR-T) therapy is an innovative therapeutic option for addressing certain recurrent or refractory hematological malignancies.
Puri Ferreros, Isabel Trapero
doaj   +1 more source

Cytokine Release Syndrome: An Overview on its Features and Management

open access: yesJournal of Pure and Applied Microbiology, 2019
Cytokine release syndrome (CRS) is a life threatening toxicity associated numerous immunotherapeutic techniques involving monoclonal antibodies, bispecific antibodies and adoptive T cell therapies. It is also referred as infusion reaction that results in
Shailza Shreshtha   +3 more
doaj   +1 more source

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