Results 271 to 280 of about 1,702,459 (293)
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The Biomedical & Life Sciences Collection, 2009
Abstract 74Cytokines are small glycoprotein mediators that are involved in every facet of immune effector function and regulation, and moreover serve to integrate immune function with other physiologic processes (e.g. metabolism, neurologic function). More than 200 cytokines have been identified. Understanding of the cytokine network has
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Abstract 74Cytokines are small glycoprotein mediators that are involved in every facet of immune effector function and regulation, and moreover serve to integrate immune function with other physiologic processes (e.g. metabolism, neurologic function). More than 200 cytokines have been identified. Understanding of the cytokine network has
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Cytokines and natural regulators of cytokines
Immunology Letters, 1994Cytokines are polypeptide or glycopeptide signalling molecules with molecular weights from 5 to 70,000 Daltons (Table 1). They act at extremely low concentrations (picomolar and femtomolar levels) as essential mediators of infectious and immunoinflammatory reactions.
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Inhaled cytokines and cytokine antagonists
Advanced Drug Delivery Reviews, 2006Cytokine and cytokine antagonist have provided novel and effective therapies for many human diseases. A number of approved cytokines including the interferons (alpha, beta and gamma), interleukin-2 (IL-2), granulocyte macrophage colony stimulating factor (GM-CSF) as well as novel cytokine antagonists have been administered by the pulmonary route for ...
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Cytokines in Cytokine Storm Syndrome
2019As the eponymous mediators of the cytokine storm syndrome, cytokines are a pleomorphic and diverse set of soluble molecules that activate or suppress immune functions in a wide variety of ways. The relevant cytokines for each CSS are likely a result of differing combinations of environmental triggers and host susceptibilities.
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2004
Cerebral ischaemia (‘stroke’) is an acute neurodegenerative disease that is one of the leading causes of death and disability in developed countries. As such it has enormous social as well as financial implications for our society and, despite intense research effort, there is as yet no effective therapy.
Allan, S., Stock, C.
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Cerebral ischaemia (‘stroke’) is an acute neurodegenerative disease that is one of the leading causes of death and disability in developed countries. As such it has enormous social as well as financial implications for our society and, despite intense research effort, there is as yet no effective therapy.
Allan, S., Stock, C.
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Cytokines and legionellosis [PDF]
Biotherapy, 1994 Recent studies have led to an enhanced understanding of the role of cell-mediated immunity and cytokines in Legionnaires' disease. In particular, the effect of interferon gamma on human mononuclear phagocyte iron metabolism and the role of iron availability of Legionella pneumophila intracellular multiplication in human monocytes has been elucidated ...
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Cytokines, Cytokine Receptors and Cytokine Antibodies: Clinical Implications
1997Cytokines are produced by almost any cell and function as important mediators of cell activation, differentiation and proliferation. These diffusibile glycoproteins appear to participate in the mediation of inflammatory as well as immune reactions, and some peptides may even influence tumor growth.
R. Caputo +3 more
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Reviews of Reproduction, 1998
There is strong evidence that cytokines and growth factors play an important role as local mediators of the actions of steroids on the endometrium to prepare it for implantation. These factors have also been shown to act in both an autocrine and paracrine manner to regulate the development of preimplantation embryos in several species.
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There is strong evidence that cytokines and growth factors play an important role as local mediators of the actions of steroids on the endometrium to prepare it for implantation. These factors have also been shown to act in both an autocrine and paracrine manner to regulate the development of preimplantation embryos in several species.
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1993
Cytokines act on eosinophils to regulate eosinophil function, with IL-5 recognised to be especially important in control of eosinopoiesis, eosinophil survival and eosinophil priming. In addition, eosinophils have the capacity to produce cytokines involved in acute and chronic inflammatory and repair processes, as well as to produce cytokines that ...
I J De Vries +6 more
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Cytokines act on eosinophils to regulate eosinophil function, with IL-5 recognised to be especially important in control of eosinopoiesis, eosinophil survival and eosinophil priming. In addition, eosinophils have the capacity to produce cytokines involved in acute and chronic inflammatory and repair processes, as well as to produce cytokines that ...
I J De Vries +6 more
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Cytokine and anti-cytokine therapy for asthma
Current Allergy and Asthma Reports, 2006Cytokines play a critical role in the pathogenesis of asthma. Asthma resolution may depend on the correction of dysregulated cytokine expression, which is a characteristic feature of this chronic inflammatory disease. It is, therefore, not surprising that attempts have been made to either block cytokines present at elevated levels or to substitute ...
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