Results 151 to 160 of about 108,055 (293)

Application of cell sorting for enhancing the performance of the cytokinesis-block micronucleus assay [PDF]

open access: gold, 2016
Ayumi Nakamura   +4 more
openalex   +1 more source

Network and Gene Set Enrichment Analysis of Adipokine Drivers of Prostate Cancer; Unravelling the Mechanistic Link Between Excess Adiposity and Prostate Cancer Risk

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Adiposity‐Based Chronic Disease (ABCD), a novel model housing obesity, insulin resistance, and adipokine‐related inflammation, increases the risk of aggressive prostate cancer (PCa), posttreatment PCa recurrence, and PCa mortality. This paper provides a new network analysis of relevant metabolic drivers to provide insight into the ...
Zachary Dovey   +2 more
wiley   +1 more source

T Cell/Mast Cell Crosstalk in the Skin of Patients Suffering From Immune‐Mediated Diseases, Focusing on Chronic Spontaneous Urticaria

open access: yesClinical and Translational Allergy, Volume 16, Issue 1, January 2026.
ABSTRACT The crosstalk between immune cells in skin lesions of numerous immune‐mediated diseases such as atopic dermatitis, psoriasis and other T cell mediated is fundamental for understanding the pathogenesis and treating these diseases. The mechanisms by which most activated immune cells such as T cells, mast cells, and neutrophils are shifted from ...
Elias Toubi   +2 more
wiley   +1 more source

Biosafety Evaluation of 6,7‐Dihydroxy‐3‐(2‐Nitrophenyl)Coumarin in Human Cells

open access: yesJournal of Applied Toxicology, Volume 46, Issue 1, Page 198-206, January 2026.
ABSTRACT Coumarins are considered a privileged scaffold in medicinal chemistry, as they may interact with biological macromolecules, presenting several pharmacological properties. Their potential makes them an object of study for the evaluation of their safety for humans, which is essential in the design of a potential drug.
Júlia Zocca Nunes de Barros   +3 more
wiley   +1 more source

Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis

open access: green, 2018
João M. Monteiro   +12 more
openalex   +2 more sources

RNAi‐mediated gene silencing of a 26S proteasome subunit increases mortality of the Japanese beetle Popillia japonica

open access: yesPest Management Science, Volume 82, Issue 1, Page 1066-1078, January 2026.
We propose the regulatory particle non‐ATPase subunit 6 of the 26S proteasome as a first good promising RNA interference target candidate to control the Japanese beetle Popillia japonica. This will help to optimize a double‐stranded RNA insecticide against this priority pest with low off‐target effects on pollinators on a gene sequence‐based prediction.
Giulia Lucetti   +10 more
wiley   +1 more source

CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo [PDF]

open access: bronze, 1997
Sally P. Wheatley   +5 more
openalex   +1 more source

Effect of Load on Non‐Muscle Myosin 2 Paralog Filaments in a Biomimetic Contractile Actin Array

open access: yesSmall, Volume 22, Issue 3, 13 January 2026.
The main paralogs of non‐muscle myosin 2 are studied on a micropatterned array of anti‐parallel actin filaments. This sarcomere‐like platform reveals myosin's load‐dependent behavior, and the resulting tension is quantified using embedded FRET sensors for both myosin and anchored actin.
Philip Bleicher   +8 more
wiley   +1 more source

Supplementary Data from FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1

open access: gold, 2023
Mijung Kwon   +10 more
openalex   +1 more source

Home - About - Disclaimer - Privacy