Results 1 to 10 of about 36,646 (146)

Eosinophil cytolysis with or without ETosis in four cases of human gastric cancer: a comparative ultrastructural study [PDF]

Exploration of Targeted Anti-tumor Therapy
The ultrastructural morphology of eosinophil cytolysis and extracellular trap cell death (ETosis) has predominantly been examined in non-neoplastic eosinophil-associated diseases, with a limited investigation in neoplasms.
Rosario Caruso, Valerio Caruso, Luciana Rigoli   +2 more
doaj   +2 more sources

Identification of autoantibodies against HIF1a in patients with anorexia nervosa and their potential role in hepatic cytolysis [PDF]

Scientific Reports
Anorexia nervosa (AN) is a severe, potentially life-threatening psychiatric disorder characterized by an intense fear of weight gain, a distorted body perception and an extern food restriction leading to an abnormally low body weight.
Ahmad Joshkon, Charlotte Reytier, Daniel Bertin, Sarah Castets, Rachel Reynaud, Flora Bat, Jean-Louis Mege, Marcel Blot-Chabaud, Patrice Darmon, Nathalie Bardin   +9 more
doaj   +2 more sources

Further Insight into the Mechanism of Human PMN Lysis following Phagocytosis of Staphylococcus aureus

Microbiology Spectrum, 2021
Staphylococcus aureus is an important human pathogen that can cause a variety of diseases ranging from mild superficial skin infections to life-threatening conditions like necrotizing pneumonia, endocarditis, and septicemia. Polymorphonuclear leukocytes (
Viktoria Rungelrath, Adeline R. Porter, Natalia Malachowa, Brett A. Freedman, Jacqueline M. Leung, Jovanka M. Voyich, Michael Otto, Scott D. Kobayashi, Frank R. DeLeo   +8 more
doaj   +1 more source

Modulation of Reoviral Cytolysis (II): Cellular Stemness

Viruses, 2023
Oncolytic viruses (OVs) are an emerging cancer therapeutic that are intended to act by selectively targeting and lysing cancerous cells and by stimulating anti-tumour immune responses, while leaving normal cells mainly unaffected.
Tarryn Bourhill, Leili Rohani, Mehul Kumar, Pinaki Bose, Derrick Rancourt, Randal N. Johnston   +5 more
doaj   +1 more source

Autophagy Protects against Eosinophil Cytolysis and Release of DNA

Cells, 2022
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis.
Stephane Esnault, Paul S. Fichtinger, Karina T. Barretto, Frances J. Fogerty, Ksenija Bernau, Deane F. Mosher, Sameer K. Mathur, Nathan Sandbo, Nizar N. Jarjour   +8 more
doaj   +1 more source

Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer

Biomolecules, 2021
The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies.
Olalekan Olanrewaju Bakare, Arun Gokul, Ruomou Wu, Lee-Ann Niekerk, Ashwil Klein, Marshall Keyster   +5 more
doaj   +1 more source

Laboratory-biochemical features of the course of chronic hepatitis C with polymorphism rs11536889 + 3725G/C of TLR-4 gene

Journal of Education, Health and Sport, 2020
Chronic HCV infection remains as a global health problem due to its wide prevalence, latent course without clinical manifestations, development of liver fibrosis with the eventual formation of cirrhosis and liver cancer, which largely leads to poor ...
T. I. Bevz, G. A. Martynyuk, L. A. Livshits, Y. M. Demchyshyn   +3 more
doaj   +1 more source

MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity

Biomolecules, 2020
Direct-acting anticancer (DAA) peptides are cytolytic peptides that show promise as novel anticancer agents. DAA peptides bind to anionic molecules that are abundant on cancer cells relative to normal healthy cells, which results in preferential killing ...
Ashley L. Hilchie, Erin E. Gill, Melanie R. Power Coombs, Reza Falsafi, Robert E. W. Hancock, David W. Hoskin   +5 more
doaj   +1 more source

Changes in the blood coagulation system that determine postoperative complications in patients with non-tumor mechanical jaundice

Вестник хирургии имени И.И. Грекова, 2021
The OBJECTIVE was to study the features of changes in the blood coagulation system that contribute to the development of postoperative complications in patients depending on the stage of non-tumor mechanical jaundice at admission.METHODS AND MATERIALS. A
V. E. Fedorov, B. S. Kharitonov, A. D. Aslanov, O. E. Logvina, M. S. Narizhnaya   +4 more
doaj   +1 more source

Serum IgG-induced microglial activation enhances neuronal cytolysis via the NO/sGC/PKG pathway in children with opsoclonus-myoclonus syndrome and neuroblastoma

Journal of Neuroinflammation, 2020
Background Opsoclonus-myoclonus syndrome (OMS) is a rare neurological disease. Some children with OMS also have neuroblastoma (NB). We and others have previously documented that serum IgG from children with OMS and NB induces neuronal cytolysis and ...
Xu Ding, Wei Yang, Qinghua Ren, Jiajian Hu, Shen Yang, Wei Han, Jing Wang, Xu Wang, Huanmin Wang   +8 more
doaj   +1 more source