Results 101 to 110 of about 44,623 (260)

Retroviral Transduction of Human Primary T Cells Followed by Real-Time T-Cell-Mediated Cancer Cell Cytolysis Analysis [PDF]

Retroviral transduction is a highly useful tool to genetically engineer hard-to-transfect human primary cells. Here, we transduce human primary T cells with a tumor-specific T cell receptor.
Debets, Reno, Thor Straten, Per, Peeters, Marlies J.W., Rahbech, Anne   +3 more
core   +1 more source

Experimental tests and modelling of complex biochemical and technical processes by taking mashing as an example:Part 3. Cytolysis

, 1998
In a third and last part, the tests and models for cytolysis during mashing are presented. The hydrolysis of the b-glucan is very important for the quality of wort and beer. An insufficient degradation can lead to processing problems (e.g.
Schwill-Miedaner, Annette, Hämäläinen, Jari; id_orcid, Einsiedler, Frank, Sommer, Karl   +3 more
core   +2 more sources

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Activation of macrophages for cytolysis of virally infected cells by monoclonal antibody to the 73-kDa lipopolysaccharide receptor

, 1994
The abilities of lipopolysaccharide (LPS) and mAb5D3 (a monoclonal antibody specific for the 73 kDa LPS receptor) to activate bone marrow culture derived macrophages (BMCM) for cytolysis of vesicular stomatitis virus infected BALB/c3T3 (VSV-3T3) and the ...
Paul A LeBlanc
core   +1 more source

Pharmacological regulation with antioxidants of hepatocyte cytolysis in acute D-galactosamine-induced intoxication

, 2020
A rat model of D-galactosamine-induced (0.3 g/kg) liver damage is used to study antioxidant and membrane-stabilizing activity of sodium selenite, vitamin E, and their combination (administered per os, daily, for 3 days before intoxication).
Illarionova T.S., Vinogradova L.F., Berezov T.T., Kharlitskaya E.V., Burobina S.S.   +4 more
core   +1 more source

Biochemical markers of liver damage in children with measles: a retrospective study

Журнал инфектологии
Liver damage in patients with measles isn’t traditionally considered a “classic” symptom. There are rare descriptions of measles-related hepatitis in the literature, but the frequency of its occurrence is unclear.
E. A. Ulanova, V. A. Greshnyakova, E. N. Kopysheva   +2 more
doaj   +1 more source

Inhibition of t cell-mediated cytolysis by 2-deoxy-d-glucose: dissociation of the inhibitory effect from glycoprotein synthesis.

, 1979
Previous studies have established that T cell-mediated cytolysis can be reversibly inhibited by the hexose analogue 2-deoxy-D-glucose (2-DG) by a mechanism which is apparently unrelated to energy depletion. The possibility that the inhibitory effect of 2-
Macdonald, H R, Cerottini, J, Cerottini, J. C., MacDonald, H. R.   +3 more
core   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Dual acellular subnormothermic machine perfusion for enhanced uterus preservation in a swine model

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In a porcine uterus transplantation model, subnormothermic machine perfusion reduced graft edema and better‐preserved post‐reperfusion contractility than static cold storage, highlighting its potential for uterus preservation, assessment, and future graft‐conditioning applications.
Lucile Cabanel, Haïzam Oubari, Bradley W. Ellis, Ludivine Dion, Vincent Lavoué, Carla Sousa, Loïc Van Dieren, Olivier Morel, Mark A. Randolph, Curtis L. Cetrulo Jr., Korkut Uygun, Alexandre G. Lellouch, Yanis Berkane, Basak E. Uygun   +13 more
wiley   +1 more source

Outcomes of therapeutic penetrating keratoplasty and deep anterior lamellar keratoplasty in acanthamoeba keratitis: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract While acanthamoeba keratitis (AK) is a sight‐threatening corneal infection, a thorough comparison of the outcomes of therapeutic penetrating keratoplasty (PK) and therapeutic deep anterior lamellar keratoplasty (DALK) is lacking. We aimed to compare clinical outcomes of PK and DALK in AK.
Gábor Tóth, Junbo Wang, Shanhe Liu, Shuailin Li, Szilárd Váncsa, Mátyás Paczkó, Tamás Kói, Péter Hegyi, Nóra Szentmáry   +8 more
wiley   +1 more source