Results 151 to 160 of about 54,277 (273)

Treatment in adult patients with acute myeloid leukemias with hyperleukocytosis at disease onset

Терапевтический архив, 2015
Aim. To evaluate the efficiency of the treatment policy for patients with acute myeloid leukemia (AML) and hyperleukocytosis (HL), which is aimed at preventing rapid hypercytolysis and massive tumor lysis (cytolysis) syndrome and/or at reducing the ...
V V Troitskaya, E N Parovichnikova, A N Sokolov, A V Kokhno, L A Kuzmina, D S Badmazhapova, Z T Fidarova, O A Gavrilina, A A Sidorova, G M Galstyan, S A Keselman, T V Gaponova, V S Galuzyak, S K Kravchenko, E O Gribanova, V G Savchenko   +15 more
doaj  

Fatal Hemorrhagic Septicemia in Common Guitarfish (Rhinobatos rhinobatos) Caused by Photobacterium damselae Subsp. damselae in a Controlled Environment

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Elasmobranchs, including sharks and rays, are commonly housed in public aquariums due to their ecological significance and educational value. The common guitarfish (Rhinobatos rhinobatos), currently listed as ‘Critically Endangered’ by the IUCN, is particularly susceptible to population declines due to overfishing and bycatch.
Giorgia Bignami, Teresa Pirollo, Perla Tedesco, Monica Caffara, Maria Letizia Fioravanti, Elena Campesi, Cristiano Da Rugna, Stefano Gridelli, Francesco Quaglio, Andrea Gustinelli   +9 more
wiley   +1 more source

Regional and Sex‐Dependent Immune Profiling Across the Colon in A Mouse Model of Ulcerative Colitis

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
At baseline, males have higher IL‐10, TH17 cytokines, and higher macrophages, neutrophils, and CD8+ cells in the medial and distal colon. Whereas females displayed increasing macrophages, lower TNF‐α, and higher IL‐1β, IL‐17A, and dendritic cells in the cecum and proximal colon.
Diane M. Tshikudi, Fola Olayinka‐Adefemi, Fazia Ait Zenati, Christine Zhang, Aaron J. Marshall, Charles N. Berstein, Jean‐Eric Ghia   +6 more
wiley   +1 more source

Targeting Cellular Lipid Rafts for Dynamic Nuclear Polarization Nuclear Magnetic Resonance

ChemBioChem, Volume 27, Issue 5, 13 March 2026.
Illuminating lipid rafts within intact cells using dynamic nuclear polarization (DNP). Targeting lipid rafts with the protein ostreolysin A allows the selective delivery of DNP‐compatible radicals, generating hyperpolarization of nuclear spins in the lipid raft. Lipid rafts serve as important platforms for membrane and signaling proteins.
Sarah A. Overall, Agnes Eck, Ancy T. Wilson, Dorothea Pinotsi, Sina J. Hartmann, Katja Packebusch, Snorri Th. Sigurdsson, Alexander B. Barnes   +7 more
wiley   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, Volume 13, Issue 17, 23 March 2026.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Clinical and biological features of acute hepatic cytolysis in dengue fever: a study from Sourô Sanou University hospital, Bobo-Dioulasso. [PDF]

IJID Reg
Jacques Z, Abdoulaye S, Tôh S, Delphine ZP, Arnaud DE, Dogbèponé S, Arsène OG, Ismael D, Mamoudou S, Apoline SK, Armel P, Appolinaire S.   +11 more
europepmc   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

CISH, a key intracellular checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints. [PDF]

Commun Biol
Cano F, Bravo-Blas A, Colombe M, Cerrato C, Venigalla RKC, Preham O, Burns E, Mortimer P, Choudhry A, Slipek N, Johnson MJ, Webber BR, Moriarity BS, Lou E, Choudhry M, Klebanoff CA, Henley T.   +16 more
europepmc   +1 more source

H-2 antigen restriction of viral infection (reply) [PDF]

, 1975
Ertl, H., Koszinowski, Ulrich H.
core   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, Volume 13, Issue 14, 9 March 2026.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source