Results 31 to 40 of about 54,277 (273)
Current concepts of the pathogenesis of non-alcoholic fatty liver disease
Сахарный диабет, 2010 Non-alcoholic fatty liver disease (NAFLD) - common chronic liver disease, characterized by pathological accumulation of fat droplets, not associatedwith alcohol.
Evgenia Pavlovna Kosobyan +1 more
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Eosinophil Extracellular Traps and Inflammatory Pathologies—Untangling the Web!
Frontiers in Immunology, 2018 Eosinophils are an enigmatic white blood cell, whose immune functions are still under intense investigation. Classically, the eosinophil was considered to fulfill a protective role against parasitic infections, primarily large multicellular helminths ...
Manali Mukherjee +2 more
doaj +1 more source
Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]
, 1980 Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Allen, H. +4 more
core +2 more sources
Direct entry of cell-penetrating peptide can be controlled by maneuvering the membrane curvature
Scientific Reports, 2021 A biomembrane's role is to be a barrier for interior cytosol from an exterior environment to execute the cell's normal biological functions. However, a water-soluble peptide called cell-penetrating peptide (CPP) has been known for its ability to directly
Kazutami Sakamoto +9 more
doaj +1 more source
Point mutations of the P53 gene, human hepatocellular carcinoma and aflatoxins [PDF]
, 1993 The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inactivation by allelic deletions or point mutations within the P53 gene as well as complex formation of wildtype p53 with cellular or viral proteins is a ...
Alexander L. Gerbes +40 more
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Mechanism of Cytolysis by Complement [PDF]
Proceedings of the National Academy of Sciences, 1972 The attack of complement is directed against the lipid moiety of the cell membrane; a single lesion at the site of fixation of complement proteins C5-C9 is responsible for lysis of a cell. There are two hypothetical models for the generation of this membrane lesion. The first of these, designated the leaky-patch model
openaire +2 more sources
Differential Endometrial Cell Sensitivity to a Cholesterol-Dependent Cytolysin Links Trueperella pyogenes to Uterine Disease in Cattle1 [PDF]
, 2014 Purulent disease of the uterus develops in 40% of dairy cows after parturition, when the epithelium of the endometrium is disrupted to expose the underlying stroma to bacteria.
Gareth Healey, Martin Sheldon
core +1 more source
Optimum marker selection of acute liver damage in rats in the experiment
RUDN Journal of Medicine, 2020 Relevance. Assessment of liver damage and functional state is one of the leading tasks of clinical and laboratory diagnostics. Traditionally used methods for determining the activity of a number of indicator enzymes in blood with relative organ ...
K. A. Popov +5 more
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Scientific Reports, 2022 Familial Mediterranean fever (FMF) patients may have hepatic cytolysis, although its origin is not formally elucidated. We aimed to evaluate liver involvement in familial Mediterranean fever (FMF) using non-invasive methods.
Samuel Deshayes +14 more
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Natural killer cell-mediated shedding of ULBP2. [PDF]
PLoS ONE, 2014 UL16 binding proteins (ULBPs) are a family of cell surface proteins that are present in transformed and stressed cells and ligands for NKG2D. Soluble NKG2D ligands have been found in sera from cancer patients with their protein concentrations correlated ...
Ruipeng Wang, Peter D Sun
doaj +1 more source