Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression. [PDF]
Human Molecular Genetics, 2002 Absence of Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein, is responsible for the Fragile X syndrome, the most common form of inherited mental retardation.
R. Mazroui +5 more
semanticscholar +2 more sources
THE ISOLATION AND PROPERTIES OF THE SPECIFIC CYTOPLASMIC GRANULES OF RABBIT POLYMORPHONUCLEAR LEUCOCYTES [PDF]
Journal of Experimental Medicine, 1960 A method has been described for isolation of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. Homogeneous suspensions of leucocytes were disrupted by lysis in 0.34 M sucrose.
Z. Cohn, J. G. Hirsch
semanticscholar +2 more sources
Blood, 1984 This study was undertaken to gain further insight into the severely impaired natural killer (NK) activity we and others have previously observed in patients with chronic lymphocytic leukemia (CLL).
N. Kay, J. Zarling
semanticscholar +2 more sources
MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties. [PDF]
EMBO Rep, 2023 Liu Q +17 more
europepmc +3 more sources
Effect of chloroquine on morphology of cytoplasmic granules in maturing human leukocytes--an ultrastructural study. [PDF]
Journal of Clinical Investigation, 1967 Bone marrow and peripheral blood from patients who had received chloroquine phosphate were studied to determine the effect of this drug on the ultrastructure of cytoplasmic granules in leukocytes.
M. Fedorko
semanticscholar +2 more sources
Erythrophagocytosis by Blasts and Numerous Cytoplasmic Granules in a Child with De Novo T-lymphoblastic Leukemia [PDF]
Turkish Journal of Hematology, 2023 Fang Long +5 more
doaj +2 more sources
Detection of tryptase in cytoplasmic granules of basophils in patients with chronic myeloid leukemia and other myeloid neoplasms. [PDF]
Blood, 2001 Tryptases are serine proteases primarily expressed in mast cells. Normal blood basophils express only trace amounts of the enzyme. However, recent immunohistochemical studies have raised the possibility that neoplastic basophils express significant ...
P. Samorapoompichit +10 more
semanticscholar +2 more sources
RNA is required for the integrity of multiple nuclear and cytoplasmic membrane‐less RNP granules
EMBO Journal, 2022 Numerous membrane‐less organelles, composed of a combination of RNA and proteins, are observed in the nucleus and cytoplasm of eukaryotic cells. These RNP granules include stress granules (SGs), processing bodies (PBs), Cajal bodies, and nuclear speckles.
C. J. Decker +3 more
semanticscholar +1 more source
PARP1 Activation Controls Stress Granule Assembly after Oxidative Stress and DNA Damage
Cells, 2022 DNA damage causes PARP1 activation in the nucleus to set up the machinery responsible for the DNA damage response. Here, we report that, in contrast to cytoplasmic PARPs, the synthesis of poly(ADP-ribose) by PARP1 opposes the formation of cytoplasmic ...
Anastasia S. Singatulina +5 more
doaj +1 more source
Ultrastructural study on the granulocytes of Uttara fowl (Gallus domesticus) [PDF]
Veterinary World, 2016 Aim: The present study was conducted to know the ultrastructural detail of the blood cells of Uttara fowl (native fowl of Uttarakhand). Materials and Methods: The experiment was conducted on 10 apparently healthy adult birds of either sex reared at the ...
Khan Idrees Mohd +3 more
doaj +1 more source