Results 171 to 180 of about 52,861 (267)

Structure‐Binding Relationship of 2‐Amino‐1,8‐Naphthyridine Dimers: Role of Linkage Positions on DNA and RNA Recognition

Chemistry – A European Journal, EarlyView.
Altering the connecting positions of two 2‐amino‐1,8‐naphthyridine units modulates binding to distinct DNA and RNA motifs. This structural variation influences molecular interactions, affecting stacking tendencies and hydrogen bonding. The positional differences determine how these molecules recognize cytosine‐rich sequences, impacting their ability to
Bimolendu Das, Satoki Kuwahara, Ryosuke Ishimaru, Eitaro Murakami, Yasue Harada, Kazuhiko Nakatani   +5 more
wiley   +1 more source

PROCEDURE FOR THE STUDY OF CERTAIN ENZYMES IN MINUTE AMOUNTS AND ITS APPLICATION TO THE INVESTIGATION OF CYTOSINE DEAMINASE

, 1948
Erwin Chargaff, Jacob Kream
openalex   +1 more source

Synergistic Effect of Herpes Simplex Virus and Cytosine Arabinoside on Human Chromosomes [PDF]

, 1971
F. Anthony O’Neill, Fred Rapp
openalex   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, EarlyView.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

ChemMedChem, EarlyView.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh   +10 more
wiley   +1 more source

Isolation of a bacterial host selective for bacteriophage T4 containing cytosine in its DNA [PDF]

, 1978
Judith Runnels, Larry Snyder
openalex   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Adenine and cytosine: Basic polarographic behavior and its interpretation [PDF]

, 1977
Timothy E. Cummings, Mark A. Jensen, Philip J. Elving   +2 more
openalex   +1 more source

Thermodynamic Insights on the Structure‐Property Relationships in Substituted Benzenes: Are the Pairwise Interactions in Tri‐Substituted Methyl‐Nitro‐Benzoic Acids Still Valid?

ChemPlusChem, EarlyView.
A comprehensive thermodynamic study of nine methyl‐nitro‐benzoic acids was carried out. By combining experimental, empirical and computational methods, a consistent and reliable set of phase transition enthalpies and enthalpies of formation was established.
José M. Silva Ferraz, Vladimir N. Emel'yanenko, Dzmitry H. Zaitsau, Artemiy A. Samarov, Bruno Brunetti, Andrea Ciccioli, Stefano Vecchio Ciprioti, Sergey P. Verevkin   +7 more
wiley   +1 more source

The Photophysics of Nucleic Acids: Consequences for the Emergence of Life

ChemSystemsChem, Volume 5, Issue 1, January 2023., 2023
Photochemical reactions in nucleic acids induced by ultraviolet (UV) radiation could have played an important role in the prebiotic selection of the building blocks of life. This Review summarizes the quantum efficiencies of the photorelaxation pathways of nucleic acids and discusses its implications for the emergence of an initial sequence pool on ...
Corinna L. Kufner, Dominik B. Bucher, Dimitar D. Sasselov   +2 more
wiley   +1 more source