Results 171 to 180 of about 136,619 (315)

Epigenome analysis of an algae-infecting giant virus reveals a unique methylation motif catalogue. [PDF]

PLoS One
Truchon AR, Zinser ER, Wilhelm SW.
europepmc   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

Electronic and Optical Sensitivity of Aluminum-Doped Boron Phosphide Monolayers for DNA Base Detection: A First-Principles Study. [PDF]

ACS Omega
Ye S, Yeh CH.
europepmc   +1 more source

DESIGN AND CONSTRUCTION A RECOMBINANT BCG CONTAINING CYTOSINE DEAMINASE SUICIDE GENE TO INCREASE THE POTENCY OF INTRAVESICAL BCG IN TREATMENT OF BLADDER CANCER

, 2008
Arsalan Barazandeh, Hossein Khanahmad, Ebrahimipour Gh.H., M Abou Alhasani, Movasagh H.A.D., Tayebeh Sohrabi   +5 more
openalex   +1 more source

Cytosine non-conversion within and between reads on unmethylated DNA from A. thaliana, D. melanogaster and phage .

Thomas James Ellis (21403016), Viktoria Nizhynska (357986), Rahul Pisupati (3852202), Almudena Mollá-Morales (21403019), Magnus Nordborg (16566)   +4 more
openalex   +1 more source

Supplementary Table 2 from Androgen Receptor Cytosine, Adenine, Guanine Repeats, and Haplotypes in Relation to Ovarian Cancer Risk

, 2023
Kathryn L. Terry, Immaculata De Vivo, Linda Titus‐Ernstoff, Mei‐Chiung Shih, Daniel W. Cramer   +4 more
openalex   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily. [PDF]

Angew Chem Int Ed Engl
Drexler L, F Fürtges T, Rudack T, Sterner R.   +3 more
europepmc   +1 more source

Data from Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase

, 2023
Chun‐Te Chen, Hirohito Yamaguchi, Hong-Jen Lee, Yi Du, Heng‐Huan Lee, Weiya Xia, Wen-Hsuan Yu, Jennifer L. Hsu, Chia‐Jui Yen, Hui‐Lung Sun, Yan Wang, Edward T.H. Yeh, Gabriel N. Hortobágyi, Mien‐Chie Hung   +13 more
openalex   +1 more source

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source