Results 221 to 230 of about 136,619 (315)

Clinical features and incidence of central nervous system involvement in patients with adult T‐cell leukaemia/lymphoma

British Journal of Haematology, EarlyView.
Summary Central nervous system (CNS) involvement is a known complication of adult T‐cell leukaemia/lymphoma (ATL), but its clinical characteristics and incidence still remain unclear. This study characterized the clinical features and incidence of CNS involvement in patients with ATL (CNS‐ATL).
Takuya Ueno, Makoto Yoshimitsu, Momone Sameshima, Taichi Nagano, Rika Akahoshi, Yusetsu Takeshita, Aya Shodai, Kodai Shima, Naosuke Arima, Yuhei Kamada, Daisuke Nakamura, Kenji Ishitsuka   +11 more
wiley   +1 more source

Modification of cytosine moieties of nucleic acids with hydrogen sulfide (nucleosides and nucleotides. XXXIV).

, 1980
Kazunobu Miura, Tohru Ueda
openalex   +2 more sources

Hypomethylating agents in vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS): A systematic review

British Journal of Haematology, EarlyView.
Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff, Roochi Trikha, Emma M. Groarke, Bhavisha A. Patel   +3 more
wiley   +1 more source

Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters. [PDF]

Nanoscale Adv
Yadavalli HC, Nagda R, Kang J, Cho M, Lou C, Yang SW, Thulstrup PW, Bjerrum MJ, Shah P.   +8 more
europepmc   +1 more source

Diagnostic and prognostic significance of internal tRNA-derived fragment glycine-glycine-cytosine (itRNAGlyGCC) expression in epithelial ovarian cancer

openalex   +1 more source

Epigenetic silencing and pharmacological inhibition of EIF5A2 foster venetoclax sensitivity in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
We show how the loss of activity of the translation initiation factor EIF5A2—either through gene hypermethylation or pharmacologic inhibition of its highly specific hypusine post‐translational modification—induces venetoclax sensitivity in acute myeloid leukaemia (AML) cells.
Eva Crespo‐García, Carlos Quero‐Dotor, Aleix Noguera‐Castells, Laia Sancho‐Vila, Laura Martinez‐Verbo, Manel Esteller   +5 more
wiley   +1 more source

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

Brain Pathology, EarlyView.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin, Yun Ning, Yang Lan, Yu‐Juan Cao, Rui‐Jiao Zhao, Hai‐Nan Li, Song Duan, Wei‐Wei Fu, Hai‐Bo Wu, Feng Wu, Xiu‐Wu Bian, Tao Luo, Xiao‐Hong Yao   +12 more
wiley   +1 more source

Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA. [PDF]

Nat Commun
Yin L, Chen Y, Shi K, Barreto Duran E, Harris RS, Aihara H.   +5 more
europepmc   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Delay in Flowering Time in <i>Arabidopsis thaliana</i> Col-0 Under Water Deficit and in the <i>ddc</i> Triple Methylation Knockout Mutant Is Correlated with Shared Overexpression of <i>BBX16</i> and <i>BBX17</i>. [PDF]

Int J Mol Sci
Vatov E, Gechev T.
europepmc   +1 more source