Results 221 to 230 of about 15,248 (235)

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity

Nature Biotechnology, 2022
Gregory A Newby, Nicholas Krasnow, Amber Mcelroy   +2 more
exaly  

Cytosine Base Editor-Mediated Multiplex Genome Editing to Accelerate Discovery of Novel Antibiotics in Bacillus subtilis and Paenibacillus polymyxa

Frontiers in Microbiology, 2021
Soo-Keun Choi, Da-Eun Jeong, Choi Soo-Keun   +2 more
exaly  

IMPROVED CYTOSINE TO GUANINE BASE EDITORS

2022
LIU DAVID, KOBLAN LUKE, ARBAB MANDANA, SHEN MAX, ANZALONE ANDREW, HUSSMANN JEFFREY   +5 more
openaire   +1 more source

Improved Dual Base Editor Systems (iACBEs) for Simultaneous Conversion of Adenine and Cytosine in the Bacterium Escherichia coli

MBio, 2023
Jae-Yean Kim, Dibyajyoti Pramanik, Rahul Mahadev Shelake   +2 more
exaly  

Effective generation of maternal genome point mutated porcine embryos by injection of cytosine base editor into germinal vesicle oocytes

Science China Life Sciences, 2020
Qingqing Cai, Junjiu Huang, Yaosheng Chen   +2 more
exaly  

Cytosine base editing in cyanobacteria by repressing archaic Type IV uracil‐DNA glycosylase

Plant Journal, 2023
Han Min Woo
exaly  

COMBINATORIAL ADENINE AND CYTOSINE DNA BASE EDITORS

2021
JOUNG J KEITH, ZHOU RONGHAO, GRUNEWALD JULIAN   +2 more
openaire   +1 more source

Artificial evolution of OsEPSPS through an improved dual cytosine and adenine base editor generated a novel allele conferring rice glyphosate tolerance

Journal of Integrative Plant Biology, 2023
exaly  

High-Efficiency Multiplexed Cytosine Base Editors for Natural Product Synthesis in Yarrowia lipolytica

ACS Synthetic Biology, 2023
Mark Blenner, Anthony Stöhr
exaly  

Characterizing and Reducing Spurious DNA Edits by CRISPR Cytosine Base Editors

2020
Cytosine Base Editors (CBEs) enable precise cytosine-to-thymine genetic mutations via APOBEC-mediated deamination of CRISPR-targeted cytosines. However, due to the natural RNA- and DNA-editing capacity of the APOBEC domains they harbor, CBEs possess the ability to create substantial pseudorandom cytosine editing events across the genomes and ...
openaire   +1 more source