Results 211 to 220 of about 25,918 (263)
The Impact of Surfactant Protein‐D Gene Polymorphism on COVID‐19 Clinical Outcomes
ABSTRACT Background COVID‐19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), presents a broad spectrum of clinical manifestations, ranging from asymptomatic cases to severe, life‐threatening respiratory complications. Pulmonary surfactant‐associated protein D (SP‐D) is a critical component of pulmonary immune defense.
Nadia Nasirzadeh Kolsari +5 more
wiley +1 more source
Mutagenicity and Repair of Acrolein Adduct to Cytosine. [PDF]
Dylewska M +3 more
europepmc +1 more source
ABSTRACT Background Sjögren's syndrome (SS) is a chronic, systemic inflammatory disorder primarily characterized by dry eyes and dry mouth, often involving multiple organ systems. The disease's heterogeneous clinical presentation and the absence of non‐invasive, specific biomarkers complicate its diagnosis and prognostic assessment.
Xinyan Zhang +4 more
wiley +1 more source
Editing mitochondrial and chloroplast genomes : Genome editing technologies for plant organelles provide new opportunities in functional genomics and breeding. [PDF]
Forner J, Bock R.
europepmc +1 more source
ABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV) has been associated with a variety of diseases and is endemic in Sub‐Saharan Africa. We performed KSHV‐whole‐genome analysis and search for APOBEC‐editing to describe genetic diversity in samples issued from an endemic region.
Gervillien Arnold Malonga +11 more
wiley +1 more source
Sequence Display enables large-scale sequence-activity datasets for rapid protein evolution. [PDF]
Cheng L +19 more
europepmc +1 more source
Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities
This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng +8 more
wiley +1 more source
Rationally and in silico guided APOBEC3F-directed CBE for enhanced PDAC genetic therapy. [PDF]
Fang Q +12 more
europepmc +1 more source
Abstract Soybean [Glycine max (L.) Merr.] yield can be reduced by 30% or more when infected with frogeye leaf spot (FLS), a fungal disease caused by Cercospora sojina K. Hara. The Rcs3 quantitative trait locus (QTL) provides strong resistance to all races of C. sojina reported in the United States and Brazil.
Samuel C. McDonald +6 more
wiley +1 more source
Clinical Trial Landscape of Gene-Edited Autologous Hematopoietic Stem Cells for Hemoglobinopathies and Immunodeficiencies. [PDF]
O'Hanlon Cohrt K, O'Dea S.
europepmc +1 more source

