Results 211 to 220 of about 15,403 (255)

APOBEC3A is the predominant global editor of cytosines in human mRNAs and in single-strand RNA viruses. [PDF]

G3 (Bethesda)
Kockler ZW, Bostan H, Klimczak LJ, Hsiao YC, Dennen MS, Cook ME, Mertz TM, Perelygina L, Kazanov MD, Li JL, Roberts SA, Gordenin DA.   +11 more
europepmc   +1 more source

Genomic Diversity of Aurochs From a Mediterranean Ice‐Age Refugium

Molecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT The aurochs, the wild ancestor of domestic cattle, was a keystone herbivore in Late Pleistocene Eurasian ecosystems and a major prey species for Palaeolithic hunter‐gatherers. Despite its significance, the genetic structure of aurochs populations that survived the Last Glacial Maximum (LGM) remains poorly understood, especially in southeastern
Vlatka Cubric‐Curik, Dinko Novosel, Zvonimir Mijadžiković, Ivana Keršić, Maja Ferenčaković, Siniša Radović, Aurélien Capitan, Mekki Boussaha, Jesper Stenderup, Ana Prohaska, Eske Willerslev, Ino Curik, Preston T. Miracle   +12 more
wiley   +1 more source

Imprecise Cas12a/ssODN‐Mediated Editing of eIF4E1 Confers Dominant‐Negative Resistance to Potato Virus Y in Solanum tuberosum

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
Efforts to mimic the pepper PVY‐resistant pvr21 allele in potato using Cas12a‐mediated single‐stranded oligodeoxynucleotide (ssODN) editing of eIF4E1, while highlighting key technical limitations, shed light on a dominant‐negative PVY resistance mechanism.
Alessandra Lucioli, Raffaela Tavazza, Attila Molnar, Vincenza Ilardi, Adéla Přibylová, Mario Tavazza   +5 more
wiley   +1 more source

Functional Characterisation of HAIRPLUS (NtHAP) Genes Involved in Trichome Development and Specialised Metabolism of Tobacco

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4640-4655, July 2026.
ABSTRACT Plant glandular trichomes are specialised epidermal structures capable of synthesising, storing and secreting numerous varieties of secondary metabolites in different classes and are central to plant defence and the biosynthesis of high‐value metabolites.
Hai Liu, Reid Farmer, Raja Payyavula, Chengalrayan Kudithipudi, Michael P. Timko   +4 more
wiley   +1 more source

Engineering Compact Base Editors by AlphaFold-Guided Mutation Scan and Escherichia coli-Based Tri-Selection. [PDF]

Adv Sci (Weinh)
Gang Son R, Kim G, Lee JK.
europepmc   +1 more source

Sequence‐Encoded Frustration Directs the Formation of Abridged G‐Quadruplex Architectures

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Programmable frustration reshapes the free‐energy surface (FES) of guanine‐quadruplex (G4) folding, stabilizing an abridged G4 and a G‐triplex intermediate. ABSTRACT Frustration—competing interactions that cannot be simultaneously optimized—shapes energy landscapes in proteins and soft matter, but has rarely been exploited as a programmable design ...
Yuncheng Qian, Mohamed Y. Ali, Andreas I. Karsisiotis, Paul Dillon, Scarlett A. Dvorkin, Peter A. C. McPherson, Mateus Webba da Silva   +6 more
wiley   +2 more sources

Mitochondrial Base Editing of the m.8993T>G Mutation Restores Bioenergetics and Neural Differentiation in Patient iPSCs. [PDF]

Genes (Basel)
Yin L, Yin A, Jones M.
europepmc   +1 more source

DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt‐Stress Priming in Soybean Seedlings

Plant, Cell &Environment, Volume 49, Issue 7, Page 3764-3776, July 2026.
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung, Qianwen Wang, Long‐Yiu Chan, Zhili Wang, Mingkun Huang, Man‐Wah Li, Fuk‐Ling Wong, Hon‐Ming Lam   +7 more
wiley   +1 more source

Regulated transformation system (RTS): sddi-mediated programmable shut-off and mode switching of base editors. [PDF]

Nucleic Acids Res
Deng J, Zhou J, Xiang H, Li X, Han X, Weng Z, Jia J, Shao Y, Sima Y, Niu M, Li D, Ouyang H, Xu B, Pang D, Yang L, Yuan H.   +15 more
europepmc   +1 more source

Enhancing Tolerance to Combined Heat and Drought Stress in Cool‐Season Grain Legumes: Mechanisms, Genetic Insights, and Future Directions

Plant, Cell &Environment, Volume 49, Issue 7, Page 3848-3870, July 2026.
ABSTRACT The increasing frequency of concurrent heat and drought stress poses a significant challenge to agricultural productivity, particularly for cool‐season grain legumes, including broad bean (Vicia Faba L.), lupin (Lupinus spp.), lentil (Lens culinaris Medik), chickpea (Cicer arietinum L.), grasspea (Lathyrus sativus L.), pea (Pisum sativum L ...
Manu Priya, Muhammad Farooq, Kadambot H. M. Siddique   +2 more
wiley   +1 more source