Results 11 to 20 of about 489,558 (321)
Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]
, 2012 Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli +10 more
core +16 more sources
Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers [PDF]
, 2017 Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein–coupled receptors, are pivotal in mediating ...
Bhargava, Aditi +7 more
core +1 more source
Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on Monoubiquitinaton
Neoplasia: An International Journal for Oncology Research, 2017 A set of high-affinity, high-specificity posttranslational modification (PTM) enrichment tools was developed to generate an unbiased snapshot of four key PTM profiles (tyrosine phosphorylation, acetylation, ubiquitination, and SUMOylation 2/3) for the ...
Henrick Horita +3 more
doaj +1 more source
Cells, 2022 Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 + 2 ...
Marta Bicka +6 more
doaj +1 more source
Models of dynamic extraction of lipid tethers from cell membranes [PDF]
, 2010 When a ligand that is bound to an integral membrane receptor is pulled, the membrane and the underlying cytoskeleton can deform before either the membrane delaminates from the cytoskeleton or the ligand detaches from the receptor.
Cuvelier D +4 more
core +1 more source
Synthesis of spectrin in avian erythroid cells: association of nascent polypeptide chains with the cytoskeleton [PDF]
, 1983 The site of synthesis of spectrin was investigated in erythroid cells from 10-day chicken embryos. After various periods of [35S]methionine incorporation the cells were lysed in a Triton X-100 (TX-100)-containing buffer and were separated into a TX-100 ...
Blikstad, Ingrid, Lazarides, Elias
core +2 more sources
cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]
, 2008 mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA +5 more
core +1 more source
Intracellular mechanochemical waves in an active poroelastic model [PDF]
, 2013 Many processes in living cells are controlled by biochemical substances regulating active stresses. The cytoplasm is an active material with both viscoelastic and liquid properties. We incorporate the active stress into a two-phase model of the cytoplasm
Alonso Muñoz, Sergio +3 more
core +2 more sources
Cells, 2019 The antigen-mediated activation of mast cells initiates signaling events leading to their degranulation, to the release of inflammatory mediators, and to the synthesis of cytokines and chemokines.
Anastasiya Klebanovych +8 more
doaj +1 more source
F1000Research, 2023 Background: Sleeping sickness is caused by the extracellular parasite Trypanosoma brucei and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder ...
Juan F. Quintana +4 more
doaj +1 more source