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The Cytoskeleton in Spermatogenesis. [PDF]
Reproduction, 2019 As germ cells progress through spermatogenesis, they undergo a dramatic transformation, wherein a single, diploid spermatogonial stem cell ultimately produces thousands of highly specialised, haploid spermatozoa. The cytoskeleton is an integral aspect of
Jessica E. M. Dunleavy +3 more
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Effect of the Rho-Kinase/ROCK Signaling Pathway on Cytoskeleton Components
Genes, 2023 The mechanical properties of cells are important in tissue homeostasis and enable cell growth, division, migration and the epithelial-mesenchymal transition. Mechanical properties are determined to a large extent by the cytoskeleton.
G. Guan, R. Cannon, D. Coates, Li Mei
semanticscholar +1 more source
The cytoskeleton and disease [PDF]
The Journal of Pathology, 2004 AbstractCytoskeletal research in recent years has revolutionized cell biology and biomedicine. The cytoskeleton spans the cytoplasm and interconnects the cell nucleus with the extracellular matrix, thereby forming a structural link between molecules involved in cell communication on the one hand, and gene expression on the other. Since the cytoskeleton
Frans C. S. Ramaekers, Fred T. Bosman
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The Bacterial Cytoskeleton [PDF]
CBE—Life Sciences Education, 2006 One of the pleasures of teaching introductory biology courses is learning new things about old, familiar subjects … such as the differences between eukaryotes and prokaryotes. For a eukaryotic cell biologist, such learning usually entails examining how bacteria function, in ways other than how they replicate and transcribe DNA and how they synthesize ...
Yu-Ling, Shih, Lawrence, Rothfield
openaire +5 more sources
Fueling the cytoskeleton – links between cell metabolism and actin remodeling
Journal of Cell Science, 2021 Attention has long focused on the actin cytoskeleton as a unit capable of organizing into ensembles that control cell shape, polarity, migration and the establishment of intercellular contacts that support tissue architecture.
Gillian DeWane +2 more
semanticscholar +1 more source
Mechanical regulation of glycolysis via cytoskeleton architecture
Nature, 2020 The mechanics of the cellular microenvironment continuously modulates cell functions such as growth, survival, apoptosis, differentiation and morphogenesis via cytoskeletal remodelling and actomyosin contractility 1 – 3 .
Jin Suk Park +11 more
semanticscholar +1 more source
Posttranslational modifications of the cytoskeleton
Cytoskeleton, 2021 The cytoskeleton plays important roles in many essential processes at the cellular and organismal levels, including cell migration and motility, cell division, and the establishment and maintenance of cell and tissue architecture.
Brittany MacTaggart, A. Kashina
semanticscholar +1 more source
Frontiers in Immunology, 2021 Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer +16 more
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Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells
Nature Biotechnology, 2020 Generation of pancreatic β cells from human pluripotent stem cells (hPSCs) holds promise as a cell replacement therapy for diabetes. In this study, we establish a link between the state of the actin cytoskeleton and the expression of pancreatic ...
N. Hogrebe +4 more
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Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers [PDF]
, 2017 Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein–coupled receptors, are pivotal in mediating ...
Bhargava, Aditi +7 more
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