Results 31 to 40 of about 349,430 (309)

Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I. [PDF]

open access: yes, 2010
Filamin and Cortexillin are F-actin crosslinking proteins in Dictyostelium discoideum allowing actin filaments to form three-dimensional networks. GAPA, an IQGAP related protein, is required for cytokinesis and localizes to the cleavage furrow during ...
Bhagyashri Burgute   +24 more
core   +2 more sources

Visualization and Manipulation of Actin Cytoskeleton with Small-Molecular Probes [PDF]

open access: yes, 2020
Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell. Here, in order to dissect the complex mechanisms of actin-related cellular functions, we introduce two powerful tools based on a new class
Keisuke, Ikawa   +14 more
core   +2 more sources

Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition

open access: yesFrontiers in Immunology, 2018
Mast cells play an effector role in innate immunity, allergy, and inflammation. Antigen-mediated activation of mast cells initiates signaling events leading to Ca2+ response and the release of inflammatory and allergic mediators from granules.
Zuzana Rubíková   +3 more
doaj   +1 more source

Kinetochore- and chromosome-driven transition of microtubules into bundles promotes spindle assembly

open access: yesNature Communications, 2022
Mitotic spindle assembly is not fully understood. This work reveals that kinetochores drive the coarsening of a uniform microtubule array into bundles, which promote spindle formation and chromosome segregation fidelity.
Jurica Matković   +6 more
doaj   +1 more source

Regulation of actin cytoskeleton via photolithographic micropatterning

open access: yesJournal of Innovative Optical Health Sciences, 2023
Actin cytoskeleton plays crucial roles in various cellular functions. Extracellular matrix (ECM) can modulate cell morphology by remodeling the internal cytoskeleton.
Fulin Xing   +9 more
doaj   +1 more source

Cell proliferation, cell shape, and microtubule and cellulose microfibril organization of tobacco BY-2 cells are not altered by exposure to near weightlessness in space [PDF]

open access: yes, 2009
The microtubule cytoskeleton and the cell wall both play key roles in plant cell growth and division, determining the plant’s final stature. At near weightlessness, tubulin polymerizes into microtubules in vitro, but these microtubules do not self ...
Emons, A.M.C.   +13 more
core   +1 more source

Cytoskeleton Dynamics

open access: yes, 2020
This volume details comprehensive state-of-the-art methods on actin microfilaments and microtubules and how they work to achieve different cellular functions in different cellular contexts.
SpringerLink (Online service)   +1 more
core   +2 more sources

Actin Cytoskeleton Straddling the Immunological Synapse between Cytotoxic Lymphocytes and Cancer Cells

open access: yesCells, 2019
The immune system is a fundamental part of the tumor microenvironment. In particular, cytotoxic lymphocytes, such as cytolytic T cells and natural killer cells, control tumor growth and disease progression by interacting and eliminating tumor cells.
Hannah Wurzer   +3 more
doaj   +1 more source

Intrinsic and Extrinsic Factors Affecting Microtubule Dynamics in Normal and Cancer Cells

open access: yesMolecules, 2020
Microtubules (MTs), highly dynamic structures composed of α- and β-tubulin heterodimers, are involved in cell movement and intracellular traffic and are essential for cell division.
Filip Borys   +3 more
doaj   +1 more source

Cytoskeletons by the sea [PDF]

open access: yesThe EMBO Reports, 2011
The ESF-EMBO meeting, 'Emergent Properties of the Cytoskeleton: Molecules to Cells', took place in October 2010 in San Feliu dex Guíxols on the eastern coast of Spain. It brought together a diverse group of international cytoskeletal researchers who gave presentations on topics from structural biology and biophysical analyses of the cytoskeleton and ...
openaire   +2 more sources

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