Results 11 to 20 of about 271,491 (266)

The Bacterial Cytoskeleton [PDF]

open access: yesCBE—Life Sciences Education, 2006
One of the pleasures of teaching introductory biology courses is learning new things about old, familiar subjects … such as the differences between eukaryotes and prokaryotes. For a eukaryotic cell biologist, such learning usually entails examining how bacteria function, in ways other than how they replicate and transcribe DNA and how they synthesize ...
Yu-Ling, Shih, Lawrence, Rothfield
openaire   +5 more sources

The cytoskeleton and disease [PDF]

open access: yesThe Journal of Pathology, 2004
AbstractCytoskeletal research in recent years has revolutionized cell biology and biomedicine. The cytoskeleton spans the cytoplasm and interconnects the cell nucleus with the extracellular matrix, thereby forming a structural link between molecules involved in cell communication on the one hand, and gene expression on the other. Since the cytoskeleton
Frans C S, Ramaekers, Fred T, Bosman
openaire   +2 more sources

The evolution of the cytoskeleton [PDF]

open access: yesJournal of Cell Biology, 2011
The cytoskeleton is a system of intracellular filaments crucial for cell shape, division, and function in all three domains of life. The simple cytoskeletons of prokaryotes show surprising plasticity in composition, with none of the core filament-forming proteins conserved in all lineages.
Wickstead, B, Gull, K
openaire   +2 more sources

Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on Monoubiquitinaton

open access: yesNeoplasia: An International Journal for Oncology Research, 2017
A set of high-affinity, high-specificity posttranslational modification (PTM) enrichment tools was developed to generate an unbiased snapshot of four key PTM profiles (tyrosine phosphorylation, acetylation, ubiquitination, and SUMOylation 2/3) for the ...
Henrick Horita   +3 more
doaj   +1 more source

The actin regulator profilin 1 is functionally associated with the mammalian centrosome

open access: yesLife Science Alliance, 2021
The actin regulator profilin 1 recently shown to control microtubule elongation at the cell periphery is found to interact with the γ-tubulin ring complex and tune centrosomal microtubule nucleation.
Michaela Nejedlá   +6 more
doaj   +1 more source

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling

open access: yesFrontiers in Immunology, 2021
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term.
Hannah Wurzer   +16 more
doaj   +1 more source

Cfap91-Dependent Stability of the RS2 and RS3 Base Proteins and Adjacent Inner Dynein Arms in Tetrahymena Cilia

open access: yesCells, 2022
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 + 2 ...
Marta Bicka   +6 more
doaj   +1 more source

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1

open access: yesCells, 2019
The antigen-mediated activation of mast cells initiates signaling events leading to their degranulation, to the release of inflammatory mediators, and to the synthesis of cytokines and chemokines.
Anastasiya Klebanovych   +8 more
doaj   +1 more source

Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids [version 2; peer review: 2 approved]

open access: yesF1000Research, 2023
Background: Sleeping sickness is caused by the extracellular parasite Trypanosoma brucei and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder ...
Juan F. Quintana   +4 more
doaj   +1 more source

The cytoskeleton in spermatogenesis [PDF]

open access: yesReproduction, 2019
Abstract As germ cells progress through spermatogenesis, they undergo a dramatic transformation, wherein a single, diploid spermatogonial stem cell ultimately produces thousands of highly specialised, haploid spermatozoa. The cytoskeleton is an integral aspect of all eukaryotic cells.
Dunleavy, J.E.M.   +3 more
openaire   +3 more sources

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