Results 21 to 30 of about 349,430 (309)

A functional link between the actin cytoskeleton and lipid rafts during budding of filamentous influenza virions [PDF]

, 2002
Morphogenesis of influenza virus is a poorly understood process that produces two types of enveloped virion: approximately 100-nm spheres and similar diameter filaments that reach 20 microm in length. Spherical particles assemble at plasma membrane lipid
Paul Digard, Simpson-Holley, Martha, McCauley, John, Debra Elton, Ellis, Darren, John McCauley, Darren Ellis, Digard, Paul, Martha Simpson-Holley, Fisher, Dawn, Elton, Debra, Dawn Fisher   +11 more
core   +1 more source

The evolution of the cytoskeleton [PDF]

Journal of Cell Biology, 2011
The cytoskeleton is a system of intracellular filaments crucial for cell shape, division, and function in all three domains of life. The simple cytoskeletons of prokaryotes show surprising plasticity in composition, with none of the core filament-forming proteins conserved in all lineages.
Wickstead, B, Gull, K
openaire   +2 more sources

Cfap91-Dependent Stability of the RS2 and RS3 Base Proteins and Adjacent Inner Dynein Arms in Tetrahymena Cilia

Cells, 2022
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 + 2 ...
Marta Bicka, Ewa Joachimiak, Paulina Urbanska, Anna Osinka, Anna Konopka, Ewa Bulska, Dorota Wloga   +6 more
doaj   +1 more source

Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+-ATPase Recycling [PDF]

, 2004
The role of the actin cytoskeleton in regulating membrane protein trafficking is complex and depends on the cell type and protein being examined. Using the epididymis as a model system in which luminal acidification is crucial for sperm maturation and ...
Pastor-Soler, Nuria, Breton, Sylvie, Brown, Christopher R., Brown, Dennis, Smith, Peter J. S., Beaulieu, Valerie, Smith, Peter J.S., Da Silva, Nicolas, Brenton, Sylvie   +8 more
core   +1 more source

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1

Cells, 2019
The antigen-mediated activation of mast cells initiates signaling events leading to their degranulation, to the release of inflammatory mediators, and to the synthesis of cytokines and chemokines.
Anastasiya Klebanovych, Vladimíra Sládková, Tetyana Sulimenko, Věra Vosecká, Zuzana Rubíková, Martin Čapek, Eduarda Dráberová, Pavel Dráber, Vadym Sulimenko   +8 more
doaj   +1 more source

KCC2 interacts with the dendritic cytoskeleton to promote spine development.

, 2007
The neuron-specific K-Cl cotransporter, KCC2, induces a developmental shift to render GABAergic transmission from depolarizing to hyperpolarizing.
Coleman, S.K., Lauri, S., Ludwig, A., Cai, C., Airaksinen, M.S., Saarma, M., Keinänen, K., Blaesse, P., Kolikova, J., Afzalov, R., Khiroug, L., Li, H., Kaila, K., Khirug, S., Rivera, C.   +14 more
core   +2 more sources

Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids [version 2; peer review: 2 approved]

F1000Research, 2023
Background: Sleeping sickness is caused by the extracellular parasite Trypanosoma brucei and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder ...
Juan F. Quintana, Matthew C. Sinton, Jay Gopalakrishnan, Praveena Chandrasegaran, Agatha Nabilla Lestari   +4 more
doaj   +1 more source

Evolution of the cytoskeleton [PDF]

BioEssays, 2007
AbstractThe eukaryotic cytoskeleton appears to have evolved from ancestral precursors related to prokaryotic FtsZ and MreB. FtsZ and MreB show 40–50% sequence identity across different bacterial and archaeal species. Here I suggest that this represents the limit of divergence that is consistent with maintaining their functions for cytokinesis and cell ...
openaire   +2 more sources

STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena

Scientific Reports, 2021
The base of the cilium comprising the transition zone (TZ) and transition fibers (TF) acts as a selecting gate to regulate the intraflagellar transport (IFT)-dependent trafficking of proteins to and from cilia.
Khodor S. Hazime, Zhu Zhou, Ewa Joachimiak, Natalia A. Bulgakova, Dorota Wloga, Jarema J. Malicki   +5 more
doaj   +1 more source

First-in-Class Colchicine-Based Visible Light Photoswitchable Microtubule Dynamics Disrupting Agent

Cells, 2023
Compounds that disrupt microtubule dynamics, such as colchicine, paclitaxel, or Vinca alkaloids, have been broadly used in biological studies and have found application in clinical anticancer medications.
Filip Borys, Piotr Tobiasz, Hanna Fabczak, Ewa Joachimiak, Hanna Krawczyk   +4 more
doaj   +1 more source