Results 21 to 30 of about 321,372 (214)
Motile cilia and eukaryotic flagella are specific cell protrusions that are conserved from protists to humans. They are supported by a skeleton composed of uniquely organized microtubules—nine peripheral doublets and two central singlets (9 × 2 + 2 ...
Marta Bicka +6 more
doaj +1 more source
Cell wall stress depolarizes cell growth via hyperactivation of RHO1 [PDF]
Cells sense and physiologically respond to environmental stress via signaling pathways. Saccharomyces cerevisiae cells respond to cell wall stress by transiently depolarizing the actin cytoskeleton.
Hall, M. N. +3 more
core +1 more source
The antigen-mediated activation of mast cells initiates signaling events leading to their degranulation, to the release of inflammatory mediators, and to the synthesis of cytokines and chemokines.
Anastasiya Klebanovych +8 more
doaj +1 more source
Background: Sleeping sickness is caused by the extracellular parasite Trypanosoma brucei and is associated with neuroinflammation and neuropsychiatric disorders, including disruption of sleep/wake patterns, and is now recognised as a circadian disorder ...
Juan F. Quintana +4 more
doaj +1 more source
SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale [PDF]
Cytoskeletal dynamics during cell behaviours ranging from endocytosis and exocytosis to cell division and movement is controlled by a complex network of signalling pathways, the full details of which are as yet unresolved.
Sobczyk, Grzegorz J. +2 more
core +1 more source
The base of the cilium comprising the transition zone (TZ) and transition fibers (TF) acts as a selecting gate to regulate the intraflagellar transport (IFT)-dependent trafficking of proteins to and from cilia.
Khodor S. Hazime +5 more
doaj +1 more source
First-in-Class Colchicine-Based Visible Light Photoswitchable Microtubule Dynamics Disrupting Agent
Compounds that disrupt microtubule dynamics, such as colchicine, paclitaxel, or Vinca alkaloids, have been broadly used in biological studies and have found application in clinical anticancer medications.
Filip Borys +4 more
doaj +1 more source
The cytoskeleton in spermatogenesis [PDF]
Abstract As germ cells progress through spermatogenesis, they undergo a dramatic transformation, wherein a single, diploid spermatogonial stem cell ultimately produces thousands of highly specialised, haploid spermatozoa. The cytoskeleton is an integral aspect of all eukaryotic cells.
Dunleavy, J.E.M. +3 more
openaire +3 more sources
Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I. [PDF]
Filamin and Cortexillin are F-actin crosslinking proteins in Dictyostelium discoideum allowing actin filaments to form three-dimensional networks. GAPA, an IQGAP related protein, is required for cytokinesis and localizes to the cleavage furrow during ...
Bhagyashri Burgute +24 more
core +1 more source
Mast cells play an effector role in innate immunity, allergy, and inflammation. Antigen-mediated activation of mast cells initiates signaling events leading to Ca2+ response and the release of inflammatory and allergic mediators from granules.
Zuzana Rubíková +3 more
doaj +1 more source

